| Type | Description |
|---|---|
| Definition | microrchidia 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-03-31 11:12:00 | Data show that the MORC3 N-terminal ATPase domain forms a dimer when bound to AMPPNP. | 27528681 |
| 2018-03-31 10:21:00 | Data indicate that Morc3 mutation leads to altered nuclear localization of the protein, and upregulation of the IFN-beta pathway, which plays a critical role in the maintenance of bone homeostasis. These findings establish Morc3 as a previously unreported regulator of cortical bone homeostasis and haematopoietic stem cells niche, accompanied by altered bone cell differentiation. | 27188231 |
| 2010-09-06 12:15:00 | MORC3 colocalizes with PML by a two-step molecular mechanism. | 20501696 |
| 2010-01-21 00:00:00 | MORC3 (microrchidia3)-ATPase activated p53 and induced cellular senescence in normal fibroblasts but not p53-/- fibroblasts | 17332504 |
| Type | IDs |
|---|---|
| Synonymous | 1110051N18Rik, AI452146, BF318192, D16Jhu32e, NXP2, Zcwcc3 |
| Gene |
UniProtKB-ID:
MORC3_MOUSE
UniprotKB:
F7BJB9
UniParc:
UPI0000215A6A
EMBL:
BC026506,
BC145705,
AC168220,
AK172896,
BC098072
Ensembl:
ENSMUSG00000039456
KO:
mmu:338467
|
| Nucleutide sequences |
EMBL-CDS:
BAD32174.1,
AAH98072.1,
AAI45706.1,
AAH26506.1
Ensembl_TRS:
ENSMUST00000044068,
ENSMUST00000202261
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000040152,
ENSMUSP00000144369
RefSeq:
XP_006523123.1,
NP_001038994.2
|
| Others |
UniRef100:
UniRef100_F7BJB9
UniRef90:
UniRef90_F7BJB9
UniRef50:
UniRef50_Q14149
UniGene:
Mm.287329
CCDS:
CCDS79490.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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