| Type | Description |
|---|---|
| Definition | NEL-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:47:00 | The cumulative chondrocyte-specific Nell-1 inactivation significantly impedes appendicular skeletogenesis resulting in dwarfism and premature osteoporosis through inhibiting Ihh signaling and predominantly altering the Ihh-PTHrP feedback loop/ | 30352124 |
| 2019-10-26 11:50:00 | a novel biological functional axis for Nell-1 and Cntnap4 in osteogenesis and, potentially, in neural development and function, is reported. | 29905970 |
| 2016-04-23 11:53:00 | Nell-1-haploinsufficient mice have normal skeletal development but undergo age-related osteoporosis, characterized by a reduction in osteoblast:osteoclast ratio and increased bone fragility. | 26082355 |
| 2015-12-05 11:43:00 | NELL-1570 has the potential to be used for cell-based or hormone-based therapy of bone regeneration. | 25376942 |
| 2014-05-31 12:21:00 | These results suggest that an oligomerization-induced conformational change in the C-terminal region of NELL1 is important for the efficient mediation of cell adhesion and spreading by NELL1. | 24563467 |
| Type | IDs |
|---|---|
| Synonymous | B230343H07Rik, l7R6 |
| Gene |
UniProtKB-ID:
NELL1_MOUSE
UniprotKB:
Q2VWQ2
UniParc:
UPI0000662EF0
EMBL:
AY622226
Ensembl:
ENSMUSG00000055409
KO:
mmu:338352
|
| Nucleutide sequences |
EMBL-CDS:
AAV41488.1
Ensembl_TRS:
ENSMUST00000081872
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080550
RefSeq:
NP_001032995.1
|
| Others |
UniRef100:
UniRef100_Q2VWQ2
UniRef90:
UniRef90_Q92832
UniRef50:
UniRef50_Q92832
UniGene:
Mm.383528
CCDS:
CCDS21309.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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