| Type | Description |
|---|---|
| Definition | NLR family pyrin domain containing 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 12:11:00 | this study shows that NLRP10 affects the stability of Abin-1 to control inflammatory responses | 30510071 |
| 2018-12-29 12:14:00 | Authors observed an important role of NLRP10 in cytokine and chemokine production as well as expression of NF-kappaB and MAPKs in CSE-exposed A549 cells. Furthermore, replenishment of A549 cell culture with recombinant IL-17A (rIL-17A) during NLRP10 knockdown rescued CSE-induced inflammatory responses. | 29501574 |
| 2018-05-26 11:20:00 | these data suggest that NLRP10 is involved in activating the ERK signalling pathway in oral epithelial cell line infected with Tannerella forsythia and Fusobacterium nucleatum | 28766990 |
| 2013-12-28 10:10:00 | Review summarize recent advances of the role of of human and murine NLRP10 in innate and adaptive immune responses. [Review] | 23562614 |
| 2013-02-02 11:58:00 | These data revealed a novel role of NLRP10 in innate immune responses towards bacterial infection and suggest that NLRP10 functions as a scaffold for the formation of the NOD1-Nodosome. | 22672233 |
| Type | IDs |
|---|---|
| Synonymous | CLR11.1, NALP10, NOD8, PAN5, PYNOD |
| Gene |
UniProtKB-ID:
NAL10_HUMAN
UniprotKB:
Q86W26
UniParc:
UPI0000167F6C
EMBL:
AY489192,
BK001110,
AY154465,
BC104957
Ensembl:
ENSG00000281166,
ENSG00000276780,
ENSG00000182261
KO:
hsa:338322
|
| Nucleutide sequences |
EMBL-CDS:
AAI04958.1,
AAO18161.1,
AAS67384.1,
DAA01243.1
Ensembl_TRS:
ENST00000612291,
ENST00000625327,
ENST00000328600
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000478480,
ENSP00000327763,
ENSP00000486762
RefSeq:
NP_789791.1,
XP_011518345.1
|
| Others |
UniRef100:
UniRef100_Q86W26
UniRef90:
UniRef90_Q86W26
UniRef50:
UniRef50_Q86W26
UniGene:
Hs.449636
CCDS:
CCDS7784.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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