| Type | Description |
|---|---|
| Definition | Collagen type IV alpha 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-13 10:28:00 | Results provide evidence that collagen IV produced in adipocytes is transported to the ovary to maintain proper germline stem cell (GSC) number in adult Drosophila females. Adipocyte-derived collagen IV acts through beta-integrin signaling to maintain normal levels of E-cadherin at the niche, thereby ensuring proper adhesion to GSCs. | 29884747 |
| 2018-09-15 11:49:00 | The results demonstrated that col4a1 mutations affect the epithelia and, consequently, secretory function of the Malpighian tubules | 29651426 |
| 2016-12-17 10:51:00 | Results of phenotypic features of Drosophila col4a1 mutants confirmed an essential role for type IV collagen in maintaining epithelial integrity, gut morphology and intestinal function and suggest that aberrant structure and function of the COL4A1 protein may also be a significant factor in modulating immunity. | 26363084 |
| 2014-10-04 10:06:00 | Data show that laminin beta and collagen IV alpha1 were involved in cardiac and muscular abnormalities. | 24935095 |
| 2012-10-06 11:36:00 | collagen IV functions to immobilize free Dpp in the Drosophila embryo | 22733779 |
| Type | IDs |
|---|---|
| Synonymous | CG25C, CG4145, CT12803, Cg25C, Cgc25, Cgc25C, Col IV alpha(1), Coll, Coll IV, DCg1, Dcg, Dcg1, Dmel\CG4145, alpha(IV)1/Cg25C, alpha1, cg25C, cg25c, col4a1, dcg1, gp125 |
| Gene |
UniProtKB-ID:
CO4A1_DROME
UniprotKB:
P08120
UniParc:
UPI000007EAD0
EMBL:
J02727,
V00200,
M28334,
M23704,
AE014134,
M96575
EnsemblGenome:
FBgn0000299
KO:
dme:Dmel_CG4145
|
| Nucleutide sequences |
EMBL-CDS:
AAB59184.1,
AAA28423.1,
AAA28422.1,
CAA23486.2,
AAF52204.1,
AAN10519.1,
AAA28404.1,
AAN10520.1
Gene_ORFName:
CG4145
EnsemblGenome_TRS:
FBtr0079003,
FBtr0079001,
FBtr0079002
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0078640,
FBpp0078642,
FBpp0078641
RefSeq:
NP_723046.1,
NP_723045.1,
NP_723044.1
|
| Others |
UniRef100:
UniRef100_P08120
UniRef90:
UniRef90_P08120
UniRef50:
UniRef50_P08120
UniGene:
Dm.5178
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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