optn - optineurin-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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336159 optn

基因描述

Type	Description
Definition	optineurin

研究结论

Date	Results	Publications
2015-06-27 12:04:00	Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics	25329564

名称对应

Type	IDs
Synonymous	si:ch211-240l19.3, wu:fj52f04, zgc:66386, zgc:77868
Gene	UniProtKB-ID: OPTN_DANRE UniprotKB: Q5RI56 UniParc: UPI00004EAD1E, UPI0000227CAE EMBL: BC055628, BC063986, BX321885 KO: dre:336159
Nucleutide sequences	EMBL-CDS: CAI11882.1, AAH63986.1, AAH55628.1 Gene_ORFName: zgc:77868, si:ch211-240l19.3, zgc:66386
Protein sequencees	RefSeq: XP_021330611.1, NP_001093536.2, XP_021330610.1
Others	UniRef100: UniRef100_Q5RI56 UniRef90: UniRef90_Q5RI56 UniRef50: UniRef50_Q5RI56 UniGene: Dr.79390

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
30818338	The selective autophagy receptors Optineurin and p62 are both required for zebrafish host resistance to mycobacterial infection. PLoS Pathog. Rui Zhang , Monica Varela , Wies Vallentgoed , Gabriel Forn-Cuni , Michiel van der Vaart , Annemarie H Meijer	2019-02-01	-
26740941	Identification of an Alu-repeat-mediated deletion of OPTN upstream region in a patient with a complex ocular phenotype. Mol Genet Genomic Med Kala F Schilter , Linda M Reis , Elena A Sorokina , Elena V Semina	2015-11-01	optn, ccdc3b, ccdc3a
26044960	Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Dis Model Mech Thean S Chew , Nuala R O'Shea , Gavin W Sewell , Stefan H Oehlers , Claire M Mulvey , Philip S Crosier , Jasminka Godovac-Zimmermann , Stuart L Bloom , Andrew M Smith , Anthony W Segal	2015-08-01	-
24683187	Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes. J. Immunol. ValÃ©rie Briolat , Luc Jouneau , Ralph Carvalho , Nuno Palha , Christelle Langevin , Philippe Herbomel , Olivier Schwartz , Herman P Spaink , Jean-Pierre Levraud , Pierre Boudinot	2014-05-01	si:dkey-225f5.5, g6pcb, ms4a17c.1, nfil3-4, unc93b1, gzm3, si:ch211-165b19.5, eif2ak2, si:ch211-165b19.8, si:ch211-165b19.9, ifit11, uba7, gbp4, irf4a, si:ch211-229n2.7, ms4a17a.17, ms4a17a.8, zmp:0000001138, ifitm1, cry1aa, map3k14a, mvb12bb, si:dkey-188i13.11, si:ch211-197g15.8, fn1a, ssbp3a, rin2, il6st, abtb2b, si:dkey-79f11.4, socs1b, si:dkey-79f11.10, si:dkey-79f11.7, si:dkey-79f11.5, ms4a17a.6, etv7, si:dkey-204f11.3, pnrc1, trafd1, zgc:162182, zgc:163136, crp7, zgc:171951, ms4a17a.4, ifnphi3, serpine1, abcb4, zgc:172295, cyp1c2, crp3, si:ch211-281g13.5, si:dkey-145c18.3, mhc1lfa, lgals9l6, si:dkeyp-9d4.2, si:ch211-71m22.3, dhx58, si:dkey-145c18.2, si:ch211-71m22.1, akt3b, si:dkey-166c18.1, si:dkey-79f11.9, cyp1b1, abca5, gak, cdkn1a, gch1, si:dkey-188i13.7, bub1, si:dkeyp-75b4.9, adm2b, nampta, tap1, si:ch211-231m23.4, vsig10l, usp18, slc16a1a, tlr7, si:ch211-122c9.5, slc25a28, si:ch211-241b2.5, znfx1, si:dkey-77f5.10, gpr37a, ms4a17c.2, si:ch211-234p6.5, cxcl11.6, cxcl11.7, tspan2b, epsti1, odc1, dusp5, blzf1, tnfrsfa, mafbb, mab21l2, her9, cebpd, scarb2
25329564	Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics. PLoS ONE Jeremiah D Paulus , Brian A Link	2014-01-01	-
23178947	Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates. J. Cell. Sci. Jelena Korac , Veronique Schaeffer , Igor Kovacevic , Albrecht M Clement , Benno Jungblut , Christian Behl , Janos Terzic , Ivan Dikic	2013-01-15	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
12477932	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team	2002-12-24	-

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