| Type | Description |
|---|---|
| Definition | Sir2 family histone deacetylase Sir2 |
| Date | Results | Publications |
|---|---|---|
| 2013-11-30 11:20:00 | Sir2 is required for Clr4 to initiate centromeric heterochromatin assembly.Sir2 deacetylates H3K14 to target Clr4 to centromeres. | 23771057 |
| 2013-06-29 11:28:00 | Sir2, together with are sufficient to ensure heterochromatin integrity and provide evidence for sequential establishment, spreading and maintenance steps in the assembly of centromeric heterochromatin. | 23572080 |
| 2010-01-21 00:00:00 | Schizosaccharomyces pombe Hst4, a homolog of histone deacetylase Sir2, participates in S-phase-specific DNA damage tolerance; it was required for the deacetylation of histone H3 core domain residue lysine 56. | 18344406 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SIR2_SCHPO
UniprotKB:
O94640
UniParc:
UPI00003B42E1
EMBL:
CU329671
EnsemblGenome:
SPBC16D10.07c
KO:
spo:SPBC16D10.07c
|
| Nucleutide sequences |
EMBL-CDS:
CAG47122.1
Gene_ORFName:
SPBC16D10.07c
EnsemblGenome_TRS:
SPBC16D10.07c.1
|
| Protein sequencees |
EnsemblGenome_PRO:
SPBC16D10.07c.1:pep
RefSeq:
NP_001018840.1
|
| Others |
UniRef100:
UniRef100_O94640
UniRef90:
UniRef90_O94640
UniRef50:
UniRef50_O94640
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of California |
3 |
| 2 |
University of Toronto |
2 |
| 3 |
Institute of Cell Biology |
2 |
| 4 |
Karolinska Institutet |
2 |
| 5 |
Columbia University |
2 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
Dong-Uk Kim |
3 |
| 2 |
Han-Oh Park |
3 |
| 3 |
Kwang-Lae Hoe |
3 |
| 4 |
Assen Roguev |
3 |
| 5 |
Nevan J Krogan |
3 |