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3360 HTR4

3360

HTR4

5-hydroxytryptamine receptor 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition 5-hydroxytryptamine receptor 4

研究结论

Date Results Publications
2020-02-01 11:18:00 Hypomethylation of the HTR4 promoter is a potential biomarker for predicting the risk of male Autism Spectrum Disorder in Chinese people. 31977880
2020-02-01 11:03:00 The down-regulation effects of IFN-alpha on p11, 5-HT1b and 5-HT4 were associated with the lysosome and ubiquitin-proteasome-mediated pathways. p11 was identified as a potent regulator to modulate the ubiquitination of 5-HT1b and 5-HT4. Therefore, it could be potential target therapies in IFN-ainduced depression 31502579
2019-10-26 12:43:00 In human large intestinal circular muscle, the intracellular pathway of 5-HT4 receptors facilitating cholinergic neurotransmission to large intestinal circular smooth muscle is controlled by phosphodiesterase 4. 28799255
2019-08-17 11:26:00 this study shows that HTR$ gene expression regulation is affected by mir-16 and mir-103 single nucleotide polymorphisms 29089619
2018-03-24 11:15:00 found that testosterone, but not estradiol, correlated negatively with global 5-HT4R levels suggesting that men with high levels of testosterone have higher cerebral serotonergic tonus. 28426945

名称对应

Type IDs
Synonymous 5-HT4, 5-HT4R
Gene
UniProtKB-ID: 5HT4R_HUMAN, A0A2D3FAF9_HUMAN
UniprotKB: Q13639, A0A2D3FAF9
UniParc: UPI000002A2CC, UPI000002A2D1, UPI000002A2CD, UPI0000000A0C, UPI0001A8C012, UPI000002A2CE, UPI000002A2CF, UPI00002323B1, UPI000002A2D0
EMBL: MF775736, AJ278980, Y12506, CH471062, AJ131724, BC095497, AJ278981, Y12507, Y10437, AC011390, Y13584, AC008627, AC114939, AM712912, AJ243213, AJ278979, AC091971, Z48150, AJ131726, Y09586, AJ011371, Y08756, MF775735, AJ131725, AJ278982, Y12505, AJ633645, BC074755
Ensembl: ENSG00000164270
KO: hsa:3360
Nucleutide sequences
EMBL-CDS: CAA70002.1, CAA88167.1, CAA73108.1, CAC20411.1, CAB71316.1, CAC22251.1, CAC22250.1, CAC22249.1, EAW61800.1, CAA70774.1, EAW61804.1, CAC79538.1, AAH95497.1, CAC22248.1, CAG17627.1, EAW61801.1, CAA09600.1, CAC79533.1, CAN84676.1, CAA73911.1, AAH74755.1, CAA73109.1, CAA73107.1, CAA71462.1, ATU46929.1, ATU46930.1
Ensembl_TRS: ENST00000520514, ENST00000521735, ENST00000362016, ENST00000360693, ENST00000522588, ENST00000377888, ENST00000517929, ENST00000521530, ENST00000631296
Protein sequencees
Ensembl_PRO: ENSP00000367120, ENSP00000435904, ENSP00000428320, ENSP00000427913, ENSP00000485747, ENSP00000430874, ENSP00000355037, ENSP00000430979, ENSP00000353915
RefSeq: NP_000861.1, NP_955525.1, NP_001035259.1, NP_001035263.1, NP_001035262.2, NP_001273339.1
Others
UniRef100: UniRef100_Q13639
UniRef90: UniRef90_Q13639
UniRef50: UniRef50_Q13639
UniGene: Hs.483773
CCDS: CCDS4291.1, CCDS34270.1, CCDS75353.1, CCDS34272.1, CCDS34273.2, CCDS34271.1

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研究热度

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