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3358 HTR2C

3358

HTR2C

5-hydroxytryptamine receptor 2C

protein-coding

Homo sapiens

基因描述

Type Description
Definition 5-hydroxytryptamine receptor 2C

研究结论

Date Results Publications
2021-02-02 13:23:00 Serotonin 5-HT2C Receptor Cys23Ser Associates with Receptor Function and Localization In Vitro. 31723224
2019-03-02 11:07:00 Our work suggests that the studied polymorphisms, 5HT1A (rs6295), 5HT1B (rs6296), and 5HT2C (rs6318), were not related to the presence of temporal lobe epilepsy (TLE), psychiatric comorbidities in TLE, and epilepsy-related factors. 29709878
2019-02-16 10:41:00 Demonstrated that a 5-HT2AR:5-HT2CR interaction occurs in cultured cells using three complementary biophysical techniques with increasing spatial resolution. Findings indicate these receptors form a close biophysical interaction within 10 nm in living cells. 30157263
2019-01-19 10:17:00 two structures of the 5-HT2C receptor in complex with the highly promiscuous agonist ergotamine and the 5-HT2A-C receptor-selective inverse agonist ritanserin at resolutions of 3.0 A and 2.7 A, respectively. 29398112
2019-01-05 11:22:00 The multivariate analysis showed the following factors as associated with the polymorphism: higher cigarette consumption, being a woman, and not having abdominal obesity. The area under the ROC curve was 0.706. An association was found between increased cigarette consumption over the years and the presence of the C allele of the rs1414334 polymorphism in the HTR2C gene 28492956

名称对应

Type IDs
Synonymous 5-HT1C, 5-HT2C, 5-HTR2C, 5HTR2C, HTR1C
Gene
UniProtKB-ID: 5HT2C_HUMAN, K9J958_HUMAN
UniprotKB: P28335, K9J958
UniParc: UPI000000126F, UPI0000458A62
EMBL: AL591402, AC007025, AK295753, AL590097, X80763, AF498983, AL355812, FJ200493, U49516, BC095543, AF208053, AC004822, M81778, AC007022
Ensembl: ENSG00000147246
KO: hsa:3358
Nucleutide sequences
EMBL-CDS: CAB59978.1, CAI41335.1, AAM21130.1, CAH70193.1, AAC71658.1, AAA60317.1, AAB40898.1, AAF35842.1, AAH95543.1, CAI41334.1, BAG58583.1, ACO54890.1
Ensembl_TRS: ENST00000371950, ENST00000371951, ENST00000276198
Protein sequencees
Ensembl_PRO: ENSP00000361018, ENSP00000361019, ENSP00000276198
RefSeq: NP_001243689.2, NP_000859.2, NP_001243690.2
Others
UniRef100: UniRef100_P28335, UniRef100_K9J958
UniRef90: UniRef90_P28335, UniRef90_A0A2J8VAD1
UniRef50: UniRef50_P28335, UniRef50_A0A2J8VAD1
UniGene: Hs.149037
CCDS: CCDS59174.1, CCDS14564.1

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