| Type | Description |
|---|---|
| Definition | 5-hydroxytryptamine receptor 2B |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:04:00 | Free energy calculations of the functional selectivity of 5-HT2B G protein-coupled receptor. | 33296400 |
| 2020-03-28 10:06:00 | This study uses over 25mus of unbiased atomistic molecular dynamics simulations to identify cholesterol interaction sites in the 5-HT1B and 5-HT2B receptors and evaluate their impact on receptor structure. | 30857969 |
| 2019-09-21 11:07:00 | We identified genome-wide significant risk loci contributing to CRA in AAs at the serotonin receptor 2B receptor gene (HTR2B), and the lead SNP, HTR2B*rs17440378, showed nominal association to aggression in the GTP cohort of cannabis-exposed subjects. | 29875475 |
| 2019-06-29 10:40:00 | In humans, mitral valve prolapse is associated with an upregulation in 5HTR2B expression and increased 5HT receptor signaling in the leaflets. | 29291394 |
| 2019-02-16 10:54:00 | findings support a role for the serotonin receptor 2B in the proliferation and migration of uveal melanoma cells, through activation of many signaling pathways such as WNT, Focal adhesion kinase and Janus | 29696577 |
| Type | IDs |
|---|---|
| Synonymous | 5-HT(2B), 5-HT-2B, 5-HT2B |
| Gene |
UniProtKB-ID:
5HT2B_HUMAN
UniprotKB:
P41595
UniParc:
UPI0000001C05
EMBL:
AY136751,
AF156160,
X77307,
AC009407,
Z36748,
AF156159,
CH471063,
BC063123,
AK313741,
AF156158
Ensembl:
ENSG00000135914
KO:
hsa:3357
|
| Nucleutide sequences |
EMBL-CDS:
CAA54513.1,
AAX93128.1,
BAG36482.1,
CAA85319.1,
AAN01277.1,
AAD39259.1,
EAW70949.1,
AAH63123.1
Ensembl_TRS:
ENST00000258400
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258400
RefSeq:
XP_005246577.1,
NP_001307687.1,
XP_006712545.1,
NP_000858.3
|
| Others |
UniRef100:
UniRef100_P41595
UniRef90:
UniRef90_P41595
UniRef50:
UniRef50_P41595
UniGene:
Hs.421649
CCDS:
CCDS2483.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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