| Type | Description |
|---|---|
| Definition | thor |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 10:56:00 | 4E-BP determines lifespan in the context of temperature changes, revealing a genetic mechanism for cold-induced longevity in this model organism. Our results suggest that the 4E-BP pathway, chiefly thought of as a nutrient sensor, may represent a master metabolic switch responding to diverse environmental factors | 28827349 |
| 2017-11-04 10:37:00 | Here, the authors show that cell autonomous insulin signaling within the Drosophila CM9 motor neuron regulates the release of neurotransmitter via alteration of the synaptic vesicle fusion machinery. This effect of insulin utilizes the FOXO-dependent regulation of the thor gene, which encodes the Drosophila homologue of the eif-4e binding protein (4eBP). | 27525480 |
| 2017-06-03 11:46:00 | GCN2 and ATF4 are important regulators of 4E-BP transcription during normal drosophila development and aging. | 27979906 |
| 2016-05-14 11:41:00 | longevity assurance mutants of chico, the Drosophila insulin receptor substrate homolog, require Drosophila d4eBP to slow aging. | 26252766 |
| 2015-12-12 11:30:00 | These results indicate that the Ccr4-Not complex controls expression of 4E-BP at multiple levels and adjusts the magnitude of the total effect. | 25793896 |
| Type | IDs |
|---|---|
| Synonymous | 153432_at, 43-BP, 4E-BP, 4E-BP1, 4EBP, 4e-BP, 4e-bp, 4eBP, 4ebp, BcDNA.HL08053, BcDNA:HL08053, CG8846, CT8705, Dm 4E-BP, Dmel\CG8846, Phas1, Thor/EIF4EBP, anon-WO0172774.158, d4E-BP, d4E-BP1, d4EBP, d4e-bp, d4eBP, dthor, eIF4E-BP, l(2)06270, l(2)k07736, l(2)k13517, pp20, thor |
| Gene |
UniProtKB-ID:
4EBP_DROME
UniprotKB:
Q9XZ56
UniParc:
UPI000007B3EF
EMBL:
AE014134,
AF132557,
AF244353
EnsemblGenome:
FBgn0261560
KO:
dme:Dmel_CG8846
|
| Nucleutide sequences |
EMBL-CDS:
AAD27856.1,
AHN54103.1,
AAF51100.1,
AAF82476.1
Gene_ORFName:
CG8846
EnsemblGenome_TRS:
FBtr0077524,
FBtr0345289
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0311456,
FBpp0077213
RefSeq:
NP_001285588.1,
NP_477295.1
|
| Others |
UniRef100:
UniRef100_Q9XZ56
UniRef90:
UniRef90_Q9XZ56
UniRef50:
UniRef50_Q9XZ56
UniGene:
Dm.3228
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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