| Type | Description |
|---|---|
| Definition | male-specific lethal 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:51:00 | RNA nucleation by MSL2 induces selective X chromosome compartmentalization. | 33208948 |
| 2020-07-04 11:03:00 | proper MSL2 positioning requires an interaction with either CLAMP or DNA to initiate dosage compensation in Drosophila males. | 31320325 |
| 2019-08-24 10:39:00 | hese are explained by physical interaction between MSL2 and CLAMP. In vivo, both factors cooperate to compete with nucleosome formation at HAS. The male-specific MSL2 thus synergises with a ubiquitous GA-repeat binding protein for refined X/autosome discrimination | 30541149 |
| 2019-08-10 11:37:00 | The data is consistent with a model where Hrp48 inhibits msl-2 translation by targeting eIF3d. | 29635389 |
| 2018-12-22 11:54:00 | the only male-specific protein within the Male-Specific Lethal complex; in addition to regulating the X chromosome, targets autosomal genes involved in patterning and morphogenesis | 30194291 |
| Type | IDs |
|---|---|
| Synonymous | CG3241, Dmel\CG3241, MSL, MSL-2, MSL2, Msl 1-3, Msl-2, Msl2, km(2)A, kmA, msl, msl2 |
| Gene |
UniProtKB-ID:
MSL2_DROME,
A4V038_DROME
UniprotKB:
P50534,
A4V038
UniParc:
UPI0000080348
EMBL:
AE014134,
Z48443,
EF634160,
L42553,
X89241,
AY128426
EnsemblGenome:
FBgn0005616
KO:
dme:Dmel_CG3241
|
| Nucleutide sequences |
EMBL-CDS:
AAA75573.1,
CAA88358.1,
CAA61529.1,
AAM75019.1,
AAF51104.1,
AAN10368.1,
ABU96715.1
Gene_ORFName:
CG3241,
CG3241,
Dmel_CG3241
EnsemblGenome_TRS:
FBtr0077570,
FBtr0077571,
FBtr0077571,
FBtr0077570
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0077260,
FBpp0077259,
FBpp0077259,
FBpp0077260
RefSeq:
NP_722907.1,
NP_523467.1
|
| Others |
UniRef100:
UniRef100_P50534
UniRef90:
UniRef90_P50534
UniRef50:
UniRef50_P50534
UniGene:
Dm.14311
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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