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3352 HTR1D

3352

HTR1D

5-hydroxytryptamine receptor 1D

protein-coding

Homo sapiens

基因描述

Type Description
Definition 5-hydroxytryptamine receptor 1D

研究结论

Date Results Publications
2020-06-20 12:51:00 significantly promotes hepatocellular carcinoma (HCC) proliferation, epithelial-mesenchymal transition, and metastasis; elevated expression level predicts poor overall survival and high recurrence probability in HCC patients 30561038
2016-07-30 10:27:00 Data show that 5-hydroxytryptamine receptor (5-HT1DR) played an important role in cell invasion via Axin1/beta-catenin/matrix metalloproteinase 7 (MMP-7) pathway. 26214021
2016-06-28 10:56:00 results suggest that 5-HT signaling participates in regulation of overall islet hormone secretion in non- diabetic individuals and over-expression of HTR1D and HTR2A may either contribute to islet dysfunction in T2D 26206285
2015-12-26 11:09:00 Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells. 25268648
2015-05-23 11:49:00 5-HT1B- and 5-HT1D-mediated signaling play an important role in the regulation of the proliferative and invasive phenotype of pancreatic cancer cells. 25170871

名称对应

Type IDs
Synonymous 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4
Gene
UniProtKB-ID: 5HT1D_HUMAN
UniprotKB: P28221
UniParc: UPI00000503DE
EMBL: BC007720, BT007027, AF498979, M89955, M81589, AL049576
Ensembl: ENSG00000179546
KO: hsa:3352
Nucleutide sequences
EMBL-CDS: AAP35673.1, AAA60315.1, AAA35491.1, AAM21126.1, AAH07720.1
Ensembl_TRS: ENST00000374619
Protein sequencees
Ensembl_PRO: ENSP00000363748
RefSeq: NP_000855.1
Others
UniRef100: UniRef100_P28221
UniRef90: UniRef90_P28221
UniRef50: UniRef50_P28221
UniGene: Hs.121482
CCDS: CCDS231.1

全选

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研究热度

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