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3350 HTR1A

3350

HTR1A

5-hydroxytryptamine receptor 1A

protein-coding

Homo sapiens

基因描述

Type Description
Definition 5-hydroxytryptamine receptor 1A

研究结论

Date Results Publications
2021-04-03 13:31:00 A functional HTR1A polymorphism, rs6295, predicts short-term response to lurasidone: confirmation with meta-analysis of other antipsychotic drugs. 31636356
2021-04-03 13:28:00 A positron emission tomography occupancy study of brexpiprazole at dopamine D2 and D3 and serotonin 5-HT1A and 5-HT2A receptors, and serotonin reuptake transporters in subjects with schizophrenia. 31847007
2020-06-27 10:47:00 5-HT1A binding in Brodmann area (BA) 41/42 did not differ between individuals who had a major depressive episode (MDE) and controls. We also found 14% higher 5-HT1A receptor binding BA 9 of individuals who had an MDE. 31120232
2020-06-27 10:36:00 For the 5-HT1A polymorphism, C carriers showed the strongest links between caregiving-related distress and sleep problems 30476041
2020-06-13 11:16:00 5-HT1A receptor gene illustrates the convergence of genetic, epigenetic and posttranscriptional mechanisms in gene expression, neurodevelopment and neuroplasticity, and major depression. 30807072

名称对应

Type IDs
Synonymous 5-HT-1A, 5-HT1A, 5HT1a, ADRB2RL1, ADRBRL1, G-21, PFMCD
Gene
UniProtKB-ID: 5HT1A_HUMAN, A8K5W4_HUMAN, Q5ZGX3_HUMAN
UniprotKB: P08908, A8K5W4, Q5ZGX3
UniParc: UPI00015DA7D2, UPI0000124F1A
EMBL: AB041403, AF498978, M83181, M28269, AK291429, CH471137, X57829, BC069159, Z11168, BC136263, X13556, AJ781317
Ensembl: ENSG00000178394
KO: hsa:3350
Nucleutide sequences
EMBL-CDS: AAA66493.1, BAA94488.1, CAA40962.1, CAA77560.1, AAH69159.1, CAA31908.1, AAA36440.1, AAM21125.1, BAF84118.1, AAI36264.1, EAW51377.1, CAH03197.1
Gene_ORFName: hCG_16836
Ensembl_TRS: ENST00000323865
Protein sequencees
Ensembl_PRO: ENSP00000316244
RefSeq: NP_000515.2
Others
UniRef100: UniRef100_P08908, UniRef100_A8K5W4
UniRef90: UniRef90_P08908
UniRef50: UniRef50_P19327
UniGene: Hs.247940
CCDS: CCDS34168.1

全选

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