| Type | Description |
|---|---|
| Definition | anterior pharynx defective 1 |
| Date | Results | Publications |
|---|---|---|
| 2010-01-21 00:00:00 | Aph-1 is required to promote cell survival in the wing imaginal disc; aph-1 mutant cells are lost either through cell death or because of a defect in cell proliferation | 19191330 |
| 2010-01-21 00:00:00 | APH-1 stabilizes the presenilin holoprotein in the complex, whereas PEN-2 is required for endoproteolytic processing of presenilin and conferring gamma-secretase activity to the complex. | 12660785 |
| 2010-01-21 00:00:00 | Aph-1 and Nct may form a subcomplex that stabilizes the Psn holoprotein at an early step in gamma-secretase assembly. | 12771124 |
| 2010-01-21 00:00:00 | the proper assembly of the Aph-1.nicastrin subcomplex with presenilin is the prerequisite for the trafficking as well as the enzymatic activity of the gamma-secretase complex and Aph-1 functions as a stabilizing scaffold in the assembly of this complex | 15644323 |
| Type | IDs |
|---|---|
| Synonymous | APH1, Aph-1, Aph1, CG2855, Dm APH-1, Dmel\CG2855, Pen-1, aph, aph1, dAph-1, l(2)23AB6, l(2)23Ag, pen-1 |
| Gene |
UniProtKB-ID:
APH1_DROME,
M9PCE6_DROME
UniprotKB:
Q9VQG2,
M9PCE6
UniParc:
UPI0000083D9E
EMBL:
AF508786,
AE014134,
AY051658
EnsemblGenome:
FBgn0031458
KO:
dme:Dmel_CG2855
|
| Nucleutide sequences |
EMBL-CDS:
AAF51212.1,
AAK93082.1,
AAN63815.1,
AGB92500.1
Gene_ORFName:
CG2855,
CG2855,
Dmel_CG2855
EnsemblGenome_TRS:
FBtr0335127,
FBtr0077716,
FBtr0077716,
FBtr0335127
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0307126,
FBpp0077400,
FBpp0077400,
FBpp0307126
RefSeq:
NP_001259963.1,
NP_608710.1
|
| Others |
UniRef100:
UniRef100_Q9VQG2
UniRef90:
UniRef90_Q9VQG2
UniRef50:
UniRef50_Q9VQG2
UniGene:
Dm.19771
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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