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33445 Drp1

33445

Drp1

Dynamin related protein 1

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Dynamin related protein 1

研究结论

Date Results Publications
2021-01-02 12:53:00 Drosophila phosphatidylinositol-4 kinase fwd promotes mitochondrial fission and can suppress Pink1/parkin phenotypes. 33085661
2019-03-09 11:36:00 The reduced expression of Parkin and HtrA2 interpret defective mitophagy leading to clustering of fragmented mitochondria and apoptotic inhibition in scrib knockdown tumors. 29360576
2017-12-23 11:54:00 Data show that short-term induction of Drp1, in midlife, is sufficient to improve organismal health and prolong lifespan. 28878259
2017-09-16 12:23:00 Study showed that exogenous expression of Drp1 could promote crawling ability, reduced the level of ATP in Drosophila brain and suppressed neuronal degeneration, suggesting that Drp1 is involved in the pathogenesis of Alzheimer disease. 28531191
2016-07-16 11:36:00 Results show that centronuclear myopathy associated Dyn2 mutants are gain-of-function mutations, and their primary effect in muscle is T-tubule disorganization, which explains the susceptibility of muscle to Dyn2 hyperactivity. 26199319

名称对应

Type IDs
Synonymous CG3210, DNM1L, DRP, DRP1, Dmel\CG3210, Dnm1/Drp1, Drp, Drp-1, drp-1, drp1, frat, l(2)22Fc, l(2)22Fd, l(2)ND2, l(2)ND3
Gene
UniProtKB-ID: Q9VQE0_DROME
UniprotKB: Q9VQE0
UniParc: UPI00000805EE
EMBL: AE014134, BT133244
EnsemblGenome: FBgn0026479
KO: dme:Dmel_CG3210
Nucleutide sequences
EMBL-CDS: AGB92483.1, AFB40589.1, AAF51235.1
Gene_ORFName: CG3210, Dmel_CG3210
EnsemblGenome_TRS: FBtr0335173, FBtr0077744
Protein sequencees
EnsemblGenome_PRO: FBpp0077424, FBpp0307166
RefSeq: NP_001259946.1, NP_608694.2
Others
UniRef100: UniRef100_Q9VQE0
UniRef90: UniRef90_Q9VQE0
UniRef50: UniRef50_Q9VQE0
UniGene: Dm.272

全选

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研究热度

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