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3344 FOXN2

3344

FOXN2

forkhead box N2

protein-coding

Homo sapiens

基因描述

Type Description
Definition forkhead box N2

研究结论

Date Results Publications
2020-08-15 17:21:00 The WT1-AS was under-expressed in cervical carcinoma and suppresses cervical cancer cell growth and aggressiveness via a miR-203a-5p/FOXN2 axis. 30720155
2019-09-14 11:42:00 The Ser365 and Ser369 sites in a conserved DSGYAS motif are critical for the degradation of FOXN2 by beta-Trcp and RSK2. Moreover, gain-of-function and loss-of-function studies show that FOXN2 impairs cell proliferation in vitro and in vivo and enhances the radiosensitivity of lung cancer. 29396548
2017-01-14 10:52:00 HTLF is a RUNX1 target whose down-regulation promotes genomic instability and correlates with complex cytogenetic abnormalities in acute myeloid leukemia patients. 26802049
2011-10-08 10:30:00 HLTF methylation may exist in gastric cardia dysplasia stages and may play important role in the development of gastric cardia adenocarcinoma. 21531217
2010-06-30 22:05:00 Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) 20379614

名称对应

Type IDs
Synonymous HTLF
Gene
UniProtKB-ID: FOXN2_HUMAN
UniprotKB: P32314
UniParc: UPI000012ADE7, UPI0000226321
EMBL: U57029, AC091485, BC063305
Ensembl: ENSG00000170802
KO: hsa:3344
Nucleutide sequences
EMBL-CDS: AAH63305.1, AAY14813.1, AAB03504.1
Ensembl_TRS: ENST00000340553
Protein sequencees
Ensembl_PRO: ENSP00000343633
RefSeq: NP_001362377.1, NP_001362376.1, XP_005264340.1, NP_001362372.1, NP_001362371.1, NP_001362375.1, NP_001362710.1, NP_001362373.1, NP_001362380.1, NP_002149.2, NP_001362381.1, NP_001362379.1, NP_001362378.1, NP_001362374.1
Others
UniRef100: UniRef100_P32314
UniRef90: UniRef90_P32314
UniRef50: UniRef50_P32314
UniGene: Hs.468478
CCDS: CCDS1838.1

全选

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研究热度

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