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33427 VGlut

33427

VGlut

Vesicular glutamate transporter

protein-coding

Drosophila melanogaster

基因描述

Type Description
Definition Vesicular glutamate transporter

研究结论

Date Results Publications
2020-05-16 11:02:00 Study established that the majority of Drosophila octopamine (OA) neurons are also glutamatergic and identify the individual contributions of each neurotransmitter on sex-specific behaviors. Males deficient for dVGLUT solely in OA-glutamate neurons also exhibit a reduction in aggression, but without a concurrent increase in inter-male courtship. Study revealed previously undetermined role for dVGLUT in OA neurons. 32097408
2017-09-02 11:47:00 This study demonstrated that Astrocytic glutamate transport regulates a Drosophila CNS synapse that lacks astrocyte ensheathment. 27073064
2011-11-26 11:26:00 Overexpression of Drosophila GLUT is sufficient to generate excitotoxic neuropathological phenotypes; therefore, reducing VGLUT levels after nervous system injury or stress may mitigate further damage. 20951206
2010-01-21 00:00:00 In the larval CNS,synaptic DVGLUT in all brain lobe neuropil compartments except for the mushroom body. Likewise in the adult CNS, glutamatergic synapses are abundant throughout all major brain structures except the mushroom body. 18302156
2010-01-21 00:00:00 DVGLUT contains 10 hydrophobic regions that completely span the membrane (TMs 1-10) & that the amino & carboxyl termini are cytosolic. between TMs 4 & 5 is an unforeseen cytosolic loop of some 50 residues. 17394549

名称对应

Type IDs
Synonymous CG9887, DV-Glut, DVGLUT, DVGluT, DVGlut, Dmel\CG9887, DvGluT, DvGlut, MFS11, VGLUT, VGluT, Vglut, dVGLUT, dVGlut, dvGluT, dvGlut, dvglut, vGLUT, vGluT, vGlut, vglut
Gene
UniProtKB-ID: Q9VQC0_DROME
UniprotKB: Q9VQC0
UniParc: UPI00004ED47A
EMBL: AE014134
EnsemblGenome: FBgn0031424
KO: dme:Dmel_CG9887
Nucleutide sequences
EMBL-CDS: AFH03525.1, AAF51256.2
Gene_ORFName: Dmel_CG9887, CG9887
EnsemblGenome_TRS: FBtr0307078, FBtr0077769, FBtr0331202
Protein sequencees
EnsemblGenome_PRO: FBpp0077449, FBpp0297921, FBpp0303629
RefSeq: NP_001245848.1, NP_608681.2
Others
UniRef100: UniRef100_Q9VQC0
UniRef90: UniRef90_Q9VQC0
UniRef50: UniRef50_Q9VQC0
UniGene: Dm.6885

全选

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研究热度

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