| Type | Description |
|---|---|
| Definition | N-deacetylase and N-sulfotransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:32:00 | Two Cases of Recessive Intellectual Disability Caused by NDST1 and METTL23 Variants. | 32878022 |
| 2020-10-03 12:52:00 | MiRNA-191 functions as an oncogene in primary glioblastoma by directly targeting NDST1. | 31364126 |
| 2017-10-21 12:14:00 | Compound heterozygous mutations in NDST1 were identified, in the heparan sulfate N deacetylatase domain of one allele and the sulfotransferase domain of the other allele. This report expands the phenotypic spectrum of Ndst1 deficiency in humans. | 28211985 |
| 2017-07-15 10:05:00 | Among the genes enriched in this screening, the authors found that TM9SF2 is critical for N-sulfation of heparan sulfate and therefore for chikungunya virus infection because it is involved in the proper localization and stability of NDST1. | 28404855 |
| 2016-05-21 12:55:00 | Our data confirm NDST1 mutations as a cause of autosomal recessive intellectual disability with a distinctive phenotype, and support an important function of NDST1 in human development. | 25125150 |
| Type | IDs |
|---|---|
| Synonymous | HSST, MRT46, NST1 |
| Gene |
UniProtKB-ID:
NDST1_HUMAN,
E7EVJ3_HUMAN,
B7Z1Q0_HUMAN,
A8K8T3_HUMAN
UniprotKB:
P52848,
E7EVJ3,
B7Z1Q0,
A8K8T3
UniParc:
UPI00015DA9E6,
UPI000012CDA5,
UPI000020CFC1,
UPI0001914AD9,
UPI000020CFC5
EMBL:
U18918,
AK292448,
BC012888,
AK293746,
AC008472,
U17970,
AC011383,
U36600,
KF510896
Ensembl:
ENSG00000070614
KO:
hsa:3340
|
| Nucleutide sequences |
EMBL-CDS:
AAH12888.1,
AAA67765.1,
AAA75281.1,
AAC27354.1,
BAH11586.1,
BAF85137.1
Ensembl_TRS:
ENST00000261797,
ENST00000523767
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261797,
ENSP00000428604
RefSeq:
NP_001287992.1,
NP_001534.1
|
| Others |
UniRef100:
UniRef100_A8K8T3,
UniRef100_E7EVJ3,
UniRef100_P52848,
UniRef100_B7Z1Q0
UniRef90:
UniRef90_P52848,
UniRef90_E7EVJ3
UniRef50:
UniRef50_O95803,
UniRef50_P52848
UniGene:
Hs.222055
CCDS:
CCDS34277.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员