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3337 DNAJB1

3337

DNAJB1

DnaJ heat shock protein family (Hsp40) member B1

protein-coding

Homo sapiens

基因描述

Type Description
Definition DnaJ heat shock protein family (Hsp40) member B1

研究结论

Date Results Publications
2021-02-27 13:51:00 HSP40 proteins use class-specific regulation to drive HSP70 functional diversity. 33177718
2021-02-06 13:57:00 Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins. 32084385
2021-02-02 13:22:00 DNAJB1-PRKACA fusions occur in oncocytic pancreatic and biliary neoplasms and are not specific for fibrolamellar hepatocellular carcinoma. 31676785
2020-07-18 12:04:00 Dimeric Hdj1 then facilitates dimerization of Hsp70 and formation of a heterotetrameric Hsp70-Hsp40 complex. Our results provide a kinetic view of the conformational cycle of Hsp70 and reveal the importance of the dynamic nature of Hsp70 for its function. 32198203
2020-04-11 11:49:00 The expression levels of TPD52 and DNAJB1 were elevated in cholangiocarcinoma (CCA) cell lines, tissues and bile samples, suggesting that these proteins may contribute to tumor pathogenesis. In addition, the expression levels of TPD52 and DNAJB1 were found to be closely associated with the clinical parameters and prognosis of patients with CCA. 31661142

名称对应

Type IDs
Synonymous HSPF1, Hdj1, Hsp40, RSPH16B, Sis1
Gene
UniProtKB-ID: DNJB1_HUMAN, Q6FHS4_HUMAN
UniprotKB: P25685, Q6FHS4
UniParc: UPI00017A82F0, UPI0000000C3A
EMBL: AC012318, AK312624, AK301817, AC009004, D49547, CH471106, CR541677, D85429, BC002352, X62421, BC019827
Ensembl: ENSG00000132002
KO: hsa:3337
Nucleutide sequences
EMBL-CDS: CAA44287.1, BAG63264.1, BAA08495.1, AAH19827.1, AAH02352.1, BAA12819.1, EAW84433.1, CAG46478.1, EAW84432.1, BAG35510.1
Gene_ORFName: hCG_1776318
Ensembl_TRS: ENST00000254322, ENST00000396969
Protein sequencees
Ensembl_PRO: ENSP00000444212, ENSP00000254322
RefSeq: XP_006722797.1, NP_001300893.1, XP_006722796.1, NP_006136.1, XP_011526258.1, NP_001287843.1
Others
UniRef100: UniRef100_P25685
UniRef90: UniRef90_P25685
UniRef50: UniRef50_P25685
UniGene: Hs.515210
CCDS: CCDS74295.1, CCDS12312.1

全选

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