| Type | Description |
|---|---|
| Definition | FERM and PDZ domain containing 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:50:00 | Uncoupling the linkage between Preso and PSD-95 attenuated the stability of this complex and suppressed the regulatory effect of Preso on the NO response. In addition, phosphorylation of NMDAR by cyclin-dependent kinase 5 (CDK5) was shown to be responsible for the Preso-mediated Ca(2+) response, which was dependent on the interaction between Preso and CDK5. | 31235685 |
| 2019-01-12 11:25:00 | The findings point to an important role of FRMPD4 in normal cognitive development and function in humans and mice, and support the hypothesis that FRMPD4 mutations cause ID by disrupting dendritic spine morphogenesis in glutamatergic neurons. | 29267967 |
| Type | IDs |
|---|---|
| Synonymous | Gm196, PKAP1, Pdzd10, Pdzk10, Preso1, preso |
| Gene |
UniProtKB-ID:
FRPD4_MOUSE,
A0A571BG68_MOUSE
UniprotKB:
A2AFR3,
A0A571BG68
UniParc:
UPI00005AC65C,
UPI0000EE055C,
UPI00005AC640,
UPI0003D74CCC
EMBL:
AL731729,
AL672186,
AL807773,
BX546498,
AL807744,
AK147370,
AK122244,
AL669945,
AK147440,
AL807785,
BX284694,
BC139429,
BX294438
Ensembl:
ENSMUSG00000049176
KO:
mmu:333605
|
| Nucleutide sequences |
EMBL-CDS:
BAE27913.1,
BAE27868.1,
BAC65526.1,
AAI39430.1
Ensembl_TRS:
ENSMUST00000239138,
ENSMUST00000112149,
ENSMUST00000238211,
ENSMUST00000112145,
ENSMUST00000238709
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000107773,
ENSMUSP00000158917,
ENSMUSP00000159190,
ENSMUSP00000107777,
ENSMUSP00000158713
RefSeq:
NP_001355865.1,
NP_001346001.1,
XP_006528952.1,
XP_011246134.1,
XP_011246136.1,
NP_001277357.1,
XP_011246135.1,
XP_006528951.1,
NP_001028502.1,
XP_036017887.1,
NP_001277356.1,
XP_006528948.1,
NP_001356163.1
|
| Others |
UniRef100:
UniRef100_A0A571BG68,
UniRef100_A2AFR3
UniRef90:
UniRef90_A2AFR3,
UniRef90_D4A3K7
UniRef50:
UniRef50_D4A3K7,
UniRef50_Q14CM0
UniGene:
Mm.426168
CCDS:
CCDS41210.1,
CCDS72470.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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