| Type | Description |
|---|---|
| Definition | amyloid beta precursor like protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:17:00 | The direct cleavage of APLP1 is a novel feature of the gamma-secretase. | 29382944 |
| 2018-07-21 11:52:00 | Results provide direct evidence that APLP1 functions as a neuronal zinc-dependent adhesion protein and allow a more detailed understanding of the molecular mechanisms driving the formation of APLP1 adhesion platforms. | 29021345 |
| 2018-05-12 11:29:00 | The results show that in cognitively normal young adults carrying APlp1 mutations showed different spontaneous brain activity patterns without cerebral structural differences. | 28987665 |
| 2015-12-05 11:10:00 | These data reveal a conserved mechanism for the binding of APP-family proteins to HS and imply a specific regulatory role of HS modifications in the biology of APP and APP-like proteins. | 25760599 |
| 2015-09-05 10:45:00 | APLP1 and APLP2, behave similarly to APP in that they both associate with assembled NMDA receptors in the endoplasmic reticulum | 25683482 |
| Type | IDs |
|---|---|
| Synonymous | APLP |
| Gene |
UniProtKB-ID:
APLP1_HUMAN
UniprotKB:
P51693
UniParc:
UPI000020215E,
UPI0000125CAD
EMBL:
AD000864,
U48437,
BC012889,
BC013850
Ensembl:
ENSG00000105290
KO:
hsa:333
|
| Nucleutide sequences |
EMBL-CDS:
AAB50173.1,
AAB96331.1,
AAH12889.1
Ensembl_TRS:
ENST00000221891,
ENST00000652533
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000221891,
ENSP00000498366
RefSeq:
NP_005157.1,
XP_016882226.1,
XP_016882227.1,
NP_001019978.1
|
| Others |
UniRef100:
UniRef100_P51693
UniRef90:
UniRef90_P51693
UniRef50:
UniRef50_P51693
UniGene:
Hs.74565
CCDS:
CCDS32997.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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