| Type | Description |
|---|---|
| Definition | transcription factor AP-2, epsilon |
| Date | Results | Publications |
|---|---|---|
| 2018-08-11 12:01:00 | work suggests that AP-2epsilon, which is expressed in late phases of differentiation, is not needed to initiate the apical-basal differentiation dichotomy but for maintaining the basal VSNs' identity. In AP-2epsilon mutants we observed a large number of cells that entered the basal program can express apical genes, our data suggest that differentiated VSNs of mice retain a notable level of plasticity. | 29928868 |
| 2016-03-26 10:38:00 | We reveal a novel role of AP-2epsilon in the regulation of gene expression in articular chondrocytes, as well as in osteoarthritis development, through modulation of Mmp13 expression and activity. | 25964075 |
| 2010-01-21 00:00:00 | Data demonstrate that transcription factor AP-2epsilon is required for olfactory bulb development, specifically the establishment of appropriate neuronal lamination. | 19580868 |
| 2010-01-21 00:00:00 | AP-2 epsilon is important for the development of the olfactory system. | 15305293 |
| 2010-01-21 00:00:00 | cloning and characterization; AP-2 epsilon is expressed most prominently in the mitral cell layer of the developing olfactory bulb; it is able to activate transcription in a binding site-dependent manner | 14572467 |
| Type | IDs |
|---|---|
| Synonymous | AI505200, AP-2e, Tcfap2e |
| Gene |
UniProtKB-ID:
AP2E_MOUSE
UniprotKB:
Q6VUP9
UniParc:
UPI0000193F2E
EMBL:
AY325902,
AL607129
Ensembl:
ENSMUSG00000042477
KO:
mmu:332937
|
| Nucleutide sequences |
EMBL-CDS:
AAQ90059.1
Ensembl_TRS:
ENSMUST00000048194
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035902
RefSeq:
NP_945198.2
|
| Others |
UniRef100:
UniRef100_Q6VUP9
UniRef90:
UniRef90_Q6VUP9
UniRef50:
UniRef50_Q6VUP9
UniGene:
Mm.331881
CCDS:
CCDS18658.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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