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332396 Kcnk18

332396

Kcnk18

potassium channel, subfamily K, member 18

protein-coding

Mus musculus

基因描述

Type Description
Definition potassium channel, subfamily K, member 18

研究结论

Date Results Publications
2021-03-06 13:30:00 Upregulation of TRESK Channels Contributes to Motor and Sensory Recovery after Spinal Cord Injury. 33256222
2021-01-23 13:01:00 TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons. 32641496
2020-09-26 13:09:00 TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses. 32929069
2020-03-07 10:42:00 Findings indicate that endogenous TWIK-related spinal cord K(+) (TRESK) activity regulates trigeminal nociception, likely through controlling the intrinsic excitability of trigeminal ganglia nociceptors. 31308053
2018-12-22 10:21:00 We compared the kinetics of Ba2+ block when channels were phosphorylated (inhibited) or dephosphorylated (activated) and in different mutants mimicking the two functional states. Neither the phosphorylation/dephosphorylation nor the point mutations influenced the development of Ba2+ block, suggesting that conformational changes of the bundle crossing region do not contribute to phosphorylation-dependent gating of TRESK. 29763475

名称对应

Type IDs
Synonymous Gm781, Tresk, Tresk-2, Trik
Gene
UniProtKB-ID: KCNKI_MOUSE
UniprotKB: Q6VV64
UniParc: UPI00001E3F16
EMBL: BC127137, AY325301, BC115705, BC104132, AK162136, BC104133, BC127136, AK139600, BC115887, AY542902
Ensembl: ENSMUSG00000040901
KO: mmu:332396
Nucleutide sequences
EMBL-CDS: AAI04133.1, BAE36746.1, AAS48426.1, AAI27138.1, AAI04134.1, BAE24080.1, AAI27137.1, AAQ91836.1, AAI15706.1, AAI15888.1
Ensembl_TRS: ENSMUST00000065204
Protein sequencees
Ensembl_PRO: ENSMUSP00000065713
RefSeq: NP_997144.1
Others
UniRef100: UniRef100_Q6VV64
UniRef90: UniRef90_Q6VV64
UniRef50: UniRef50_Q6VV64
UniGene: Mm.329947
CCDS: CCDS29934.1

全选

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