| Type | Description |
|---|---|
| Definition | Adaptor Protein complex 2, alpha subunit |
| Date | Results | Publications |
|---|---|---|
| 2019-05-11 10:04:00 | Prd1, alpha-Adaptin, and Unc-104 act in a common pathway to promote dendrite pruning by down-regulating Neuroglian protein. | 30142146 |
| 2016-09-24 10:55:00 | The adaptor protein 2 (AP-2) complex binds to a motif in the cytoplasmic tail of Crumbs that overlaps with the binding site of Stardust, a protein known to stabilize Crumbs on the surface. | 26527400 |
| 2012-07-28 11:33:00 | Interaction of Notch signaling modulator Numb with alpha-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells. | 22474327 |
| 2010-01-21 00:00:00 | Numb and alpha-Adaptin regulate Sanpodo endocytosis to specify cell fate in Drosophila external sensory organs. | 16113648 |
| 2010-01-21 00:00:00 | Numb polarizes the distribution of alpha-Adaptin, involved in receptor-mediated endocytosis. Alpha-Adaptin mutations not binding to Numb don't localize asymmetrically and cause defects in asymmetric cell division. | 12194853 |
| Type | IDs |
|---|---|
| Synonymous | AP-2, AP2, Ada, Alpha-Adaptin, CG31654, CG4260, D-Ada, D-alphaAda, Dmel\CG4260, MENE (2L)-A, MENE(2L)-A, ada, alpha, alpha-Ada, alpha-Adaptin, alpha-ada, alpha-adaptin, alphaAda, alphaada, apl3, cg4260, dAP-2a, l(2)06694, l(2)SH0460, l(2)SH2 0460 |
| Gene |
UniProtKB-ID:
AP2A_DROME,
E8NH12_DROME
UniprotKB:
P91926,
E8NH12
UniParc:
UPI00001E10C8,
UPI00000073E1
EMBL:
Y11104,
AE014134,
BT032839,
Y13092,
BT125866,
BT003458
EnsemblGenome:
FBgn0264855
KO:
dme:Dmel_CG4260
|
| Nucleutide sequences |
EMBL-CDS:
AAS64634.1,
AAF56103.2,
CAA71991.1,
ACD81853.1,
AAO39461.1,
CAA73533.1,
ADU79254.1
Gene_ORFName:
CG4260
EnsemblGenome_TRS:
FBtr0089488,
FBtr0089489,
FBtr0089489
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0088490,
FBpp0088945,
FBpp0088945
RefSeq:
NP_476819.2,
NP_995607.1
|
| Others |
UniRef100:
UniRef100_P91926,
UniRef100_E8NH12
UniRef90:
UniRef90_P91926
UniRef50:
UniRef50_P91926
UniGene:
Dm.246
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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