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330962 Slc51b

330962

Slc51b

solute carrier family 51, beta subunit

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 51, beta subunit

研究结论

Date Results Publications
2017-07-15 10:12:00 Data suggest that transport of bile acid taurocholate is retained when OstB is truncated to contain only the transmembrane domain with 15 additional residues on each side and co-expressed with intact OstA (organic solute transporter alpha subunit); shorter fragments of OstB are inactive. 28455390
2010-01-21 00:00:00 Co-expression of mouse Ostalpha-Ostbeta, but not the individual subunits, stimulated Na(+)-independent bile acid uptake and the apical-to-basolateral transport of taurocholate 15563450
2010-01-21 00:00:00 OSTalpha and OSTbeta mRNA levels were induced in the adrenals and kidneys of wild-type, but not FXR-/-, mice 16251721
2010-01-21 00:00:00 The mouse Ostalpha and Ostbeta promoters are unusual in that they contain functional FXR and LRH elements, which mediate, respectively, positive and negative feedback regulation by bile acids. 16357058
2010-01-21 00:00:00 These data indicate that Ostalpha-Ostbeta is essential for intestinal bile acid transport in mice. 18292224

名称对应

Type IDs
Synonymous Ostb
Gene
UniProtKB-ID: OSTB_MOUSE
UniprotKB: Q80WK2
UniParc: UPI0000192180
EMBL: AK002463, BC115606, AY279396, AK004188, BC115607
Ensembl: ENSMUSG00000053862
KO: mmu:330962
Nucleutide sequences
EMBL-CDS: BAE20415.1, AAP23994.1, AAI15607.1, AAI15608.1, BAE20418.1
Ensembl_TRS: ENSMUST00000065894
Protein sequencees
Ensembl_PRO: ENSMUSP00000064494
RefSeq: NP_849264.1
Others
UniRef100: UniRef100_Q80WK2
UniRef90: UniRef90_Q80WK2
UniRef50: UniRef50_Q80WK2
UniGene: Mm.335247
CCDS: CCDS23291.1

全选

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研究热度

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