| Type | Description |
|---|---|
| Definition | Rho GTPase activating protein 32 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 11:35:00 | Our results suggest that PX-RICS-mediated GABAAR trafficking is a key target for GABAergic plasticity and its dysfunction leads to atypical emotional processing underlying autism. | 30045817 |
| 2016-08-06 11:15:00 | PX-RICS-deficient mice exhibit ASD-like social behaviours and ASD-related comorbidities. PX-RICS-deficient neurons show reduced surface gamma-aminobutyric acid type A receptor (GABAAR) levels and impaired GABAAR-mediated synaptic transmission. | 26979507 |
| 2015-04-18 10:52:00 | leptin stimulates the MAPK pathways and CREB dependent transcription. This then leads to an increase in miR132 that suppresses expression of the Rac1 inhibitor p250GAP, thus activating Rac1 and promoting synaptogenesis. | 24877561 |
| 2014-03-15 11:33:00 | Overexpression of p250GAP abolishes brain-derived neurotrophic factor (BDNF)-induced branching. | 24431455 |
| 2013-05-25 12:11:00 | Cdh1-APC together with the RhoA regulators p250GAP and Smurf1 controls axon growth in the mammalian brain | 23226367 |
| Type | IDs |
|---|---|
| Synonymous | 3426406O18Rik, Gc-gap, Grit, Px-rics, Rics, mKIAA0712, p200Rhogap, p250Gap |
| Gene |
UniProtKB-ID:
RHG32_MOUSE
UniprotKB:
Q811P8
UniParc:
UPI00000062D2,
UPI000178DE7B
EMBL:
AC134607,
AK173008,
BC132390,
AY194286,
BC138042
Ensembl:
ENSMUSG00000041444
KO:
mmu:330914
|
| Nucleutide sequences |
EMBL-CDS:
AAI32391.1,
AAI38043.1,
AAO43676.1,
BAD32286.1
Ensembl_TRS:
ENSMUST00000168954,
ENSMUST00000182802,
ENSMUST00000174641
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133898,
ENSMUSP00000138145,
ENSMUSP00000128448
RefSeq:
XP_036010973.1,
XP_006510508.1,
XP_006510505.1,
XP_036010972.1,
NP_796353.3,
XP_030100286.1,
XP_030100285.1,
NP_001357886.1,
NP_001357887.1,
NP_001182561.1
|
| Others |
UniRef100:
UniRef100_Q811P8
UniRef90:
UniRef90_Q811P8
UniRef50:
UniRef50_A7KAX9
UniGene:
Mm.46683
CCDS:
CCDS22951.3,
CCDS57666.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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