| Type | Description |
|---|---|
| Definition | deoxyhypusine synthase |
| Date | Results | Publications |
|---|---|---|
| 2015-10-24 11:30:00 | Deletion of hypusine modification enzymes ( deoxyhypusine synthase and deoxyhypusine hydroxylase )exerts strong phenotypes. eIF-5A2-deleted animals are viable and fertile. | 26037925 |
| 2014-03-08 11:16:00 | The results suggest a previously unrecognized role for deoxyhypusine synthase in promoting T cell proliferation and differentiation via regulation of CD25. | 24196968 |
| 2012-06-02 10:21:00 | knockout of either the eIF5A-1 gene (Eif5a) or of the deoxyhypusine synthase gene (Dhps) caused early embryonic lethality in mice, indicating the essential nature of both eIF5A-1 and deoxyhypusine synthase in mammalian development | 21850436 |
| 2011-08-13 10:21:00 | Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. | 21389784 |
| 2011-01-15 10:49:00 | DHS is required for the ongoing production of proteins, particularly CHOP, in response to ER stress in the beta cell. | 20956533 |
| Type | IDs |
|---|---|
| Synonymous | Dhs |
| Gene |
UniProtKB-ID:
DHYS_MOUSE
UniprotKB:
Q3TXU5
UniParc:
UPI00001E4404
EMBL:
AC163703,
AK159104
Ensembl:
ENSMUSG00000060038
KO:
mmu:330817
|
| Nucleutide sequences |
EMBL-CDS:
BAE34820.1
Ensembl_TRS:
ENSMUST00000078665
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000077733
RefSeq:
NP_001034603.1
|
| Others |
UniRef100:
UniRef100_Q3TXU5
UniRef90:
UniRef90_Q3TXU5
UniRef50:
UniRef50_P49366
UniGene:
Mm.193086,
Mm.456030
CCDS:
CCDS22492.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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