| Type | Description |
|---|---|
| Definition | sidekick cell adhesion molecule 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-10-06 10:24:00 | The results suggest that the Ig-like domains and the fibronectin III (FnIII) domains of Sidekicks play different roles in cell adhesion. The Ig-like domains mediate the homophilic transinteractions bridging adjacent cells, while the FnIII domains interact with membranes, resulting in a tight adhesion interface between cells | 30150416 |
| 2017-12-16 11:31:00 | Here the authors report crystal structures of Sdk1 and Sdk2 ectodomain regions, revealing similar homodimers mediated by the four N-terminal immunoglobulin domains (Ig1-4), arranged in a horseshoe conformation. | 27644106 |
| 2010-09-06 12:21:00 | Data conclude that the up-regulation of sdk-1 in podocytes is an important pathogenic factor in glomerulosclerosis and that the mechanism involves disruption of the actin cytoskeleton possibly via alterations in MAGI-1 function. | 20562105 |
| 2010-01-21 00:00:00 | sidekick is expressed in ureteric bud and ureteric bud-derived tissues and may play a role in branching morphogenesis | 15213259 |
| 2010-01-21 00:00:00 | results establish that the first and second immunoglobulin domains of sidekick-1 and -2 are necessary and sufficient to mediate and target homophilic adhesion | 15703275 |
| Type | IDs |
|---|---|
| Synonymous | 5330440E10, 6720466O15Rik |
| Gene |
UniProtKB-ID:
SDK1_MOUSE
UniprotKB:
Q3UH53
UniParc:
UPI00006A7812,
UPI00005AC68E
EMBL:
AK147578,
AY353236,
AK035225,
BC060237,
AK032883,
AK148648
Ensembl:
ENSMUSG00000039683
KO:
mmu:330222
|
| Nucleutide sequences |
EMBL-CDS:
BAC28986.1,
BAE28630.1,
AAQ57662.1,
BAE28004.1,
BAC28069.1,
AAH60237.1
Ensembl_TRS:
ENSMUST00000085774,
ENSMUST00000074546
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000082928,
ENSMUSP00000074133
RefSeq:
NP_808547.3,
XP_006504775.1
|
| Others |
UniRef100:
UniRef100_Q3UH53
UniRef90:
UniRef90_Q3UH53
UniRef50:
UniRef50_Q3UH53
UniGene:
Mm.151931,
Mm.406697
CCDS:
CCDS39360.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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