| Type | Description |
|---|---|
| Definition | DnaJ heat shock protein family (Hsp40) member B2 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-18 13:41:00 | DNAJB2 expression in healthy human palatal mucosa is strongly negatively correlated with serum cotinine levels | 31682009 |
| 2017-11-11 11:36:00 | Study describes the identi fi cation of the fi rst deletion reported at the DNAJB2 locus, further expanding its phenotypic and genotypic spectrums as well as its disease-associated mechanisms with spinal muscular atrophy and parkinsonism. | 27449489 |
| 2017-09-16 11:20:00 | Our results disclose a novel interplay between ubiquitin- and phosphorylation-dependent signalling, and represent the first report of a regulatory mechanism for UIM-dependent function. They also suggest that CK2 inhibitors could release the full neuroprotective potential of HSJ1, and deserve future interest as therapeutic strategies for neurodegenerative disease. | 28031292 |
| 2015-01-03 12:27:00 | The results of this study confirm that HSJ1 mutations are a rare but detectable cause of autosomal recessive dHMN and CMT2. | 25274842 |
| 2014-04-19 10:37:00 | HSJ1a acts on mutant SOD1 through a combination of chaperone, co-chaperone and pro-ubiquitylation activity. | 24023695 |
| Type | IDs |
|---|---|
| Synonymous | CMT2T, DSMA5, HSJ-1, HSJ1, HSPF3 |
| Gene |
UniProtKB-ID:
DNJB2_HUMAN
UniprotKB:
P25686
UniParc:
UPI000000DBA9,
UPI000000DCD8
EMBL:
AC114803,
S37374,
S37375,
BT007088,
X63368,
AK312723,
AK292761,
CH471063,
BC047056,
BC011609
Ensembl:
ENSG00000135924
KO:
hsa:3300
|
| Nucleutide sequences |
EMBL-CDS:
AAH47056.1,
BAF85450.1,
CAA44969.2,
BAG35597.1,
AAA09035.1,
EAW70722.1,
CAA44968.2,
AAP35751.1,
AAY24037.1,
AAH11609.1,
AAA09034.1
Ensembl_TRS:
ENST00000336576,
ENST00000392086
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000375936,
ENSP00000338019
RefSeq:
NP_006727.2,
NP_001034639.1
|
| Others |
UniRef100:
UniRef100_P25686
UniRef90:
UniRef90_P25686
UniRef50:
UniRef50_P25686
UniGene:
Hs.77768
CCDS:
CCDS2439.1,
CCDS46519.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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