| Type | Description |
|---|---|
| Definition | zelda |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 12:01:00 | We conclude that in B. germanica, Zelda strictly activates the zygotic genome, within the MZT, a role conserved in more derived endopterygote insects. In B. germanica, zelda is expressed during MZT, whereas in D. melanogaster and T. castaneum it is expressed beyond this transition. | 30993896 |
| 2020-05-23 12:00:00 | Zld modifies probability of transcriptional activation, the timing of this activation, and the rate at which transcription occurs. This effective rate increase is due to an increased accumulation of Dl at the site of transcription, suggesting that transcription factor "hubs" induced by Zld functionally regulate transcription. | 30982648 |
| 2019-07-20 12:52:00 | Continued Zelda activity is required throughout genome activation. Zelda binds DNA in the context of nucleosomes and suggest that this allows Zelda to occupy the genome despite the rapid division cycles in the early embryo. | 30797686 |
| 2019-06-08 12:54:00 | Study reports that Drosophila protein Jumu binds N6-methyladenine (6mA)-marked DNA and acts as a maternal factor to regulate the maternal-to-zygotic transition and finds that zelda encoding the pioneer factor Zelda is marked by 6mA. Genetic assays suggest that Jumu controls the proper zygotic genome activation in early embryos, at least in part, by regulating zelda expression. | 31101825 |
| 2019-04-27 12:02:00 | Findings show that both factors form dynamic subnuclear hubs, and that Bicoid binding is enriched within Zelda hubs. | 30589412 |
| Type | IDs |
|---|---|
| Synonymous | CG12701, Dmel\CG12701, EP1344, VFL, Vfl, ZLD, Zelda, Zld, l(1)G0225, l(1)G0353, l(1)G0427, vfl |
| Gene |
UniProtKB-ID:
Q9VWC6_DROME,
X2BZL0_DROME,
M9NES1_DROME
UniprotKB:
Q9VWC6,
X2BZL0,
M9NES1
UniParc:
UPI0000076892,
UPI000237F7C0,
UPI000237F7BF
EMBL:
BT132946,
AE014298
EnsemblGenome:
FBgn0259789
KO:
dme:Dmel_CG12701
|
| Nucleutide sequences |
EMBL-CDS:
AEW31265.1,
AHN59936.1,
AAN09519.1,
AAF49020.1,
AFH07480.1,
AFH07481.1
Gene_ORFName:
Dmel_CG12701,
CG12701,
CG12701,
Dmel_CG12701,
Dmel_CG12701,
CG12701
EnsemblGenome_TRS:
FBtr0074807,
FBtr0345014,
FBtr0074808,
FBtr0344733,
FBtr0307537
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0074576,
FBpp0311265,
FBpp0074577,
FBpp0311065,
FBpp0300192
RefSeq:
NP_608356.1,
NP_001245769.1,
NP_001245768.1,
NP_001285466.1,
NP_728304.1
|
| Others |
UniRef100:
UniRef100_X2BZL0,
UniRef100_Q9VWC6,
UniRef100_M9NES1
UniRef90:
UniRef90_Q9VWC6
UniRef50:
UniRef50_Q9VWC6
UniGene:
Dm.22844
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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