| Type | Description |
|---|---|
| Definition | heat shock transcription factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 12:08:00 | The results expand the spectrum of HSF4 mutations causing congenital cataracts. | 30143024 |
| 2019-01-26 10:45:00 | Ectopic UAP56 upregulated HSF4-controlled HSP25 and alpha B-crystallin proteins expression, while knocking down UAP56 by shRNA reversed it. | 29164525 |
| 2018-12-22 10:07:00 | We have identified a novel mutation in HSF4 in a large British pedigree causing dominant congenital lamellar cataract | 29243736 |
| 2018-07-07 10:03:00 | High HSF4 expression is an independent indicator of poor overall survival and recurrence free survival in patients with primary colorectal cancer. | 29131521 |
| 2018-06-09 10:56:00 | In the cultured human lens epithelial cells, HSF4 could stabilize and retain p53 in the nucleus to activate its target genes such as fas cell surface death receptor (Fas) and Bcl-2-associated X apoptosis regulator (Bax). | 28981088 |
| Type | IDs |
|---|---|
| Synonymous | CTM, CTRCT5 |
| Gene |
UniProtKB-ID:
HSF4_HUMAN,
A0A024R6X7_HUMAN
UniprotKB:
Q9ULV5,
A0A024R6X7
UniParc:
UPI0000366B51,
UPI000013D4A0
EMBL:
D87673,
AB029347,
AB029348,
CH471092,
AC074143
Ensembl:
ENSG00000102878
KO:
hsa:3299
|
| Nucleutide sequences |
EMBL-CDS:
BAA84582.1,
BAA13433.1,
BAA84581.1,
EAW83084.1,
EAW83083.1,
EAW83085.1
Gene_ORFName:
hCG_2040102,
hCG_2025835
Ensembl_TRS:
ENST00000584272,
ENST00000521374
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000463706,
ENSP00000430947
RefSeq:
NP_001361604.1,
NP_001529.2,
NP_001035757.1,
NP_001361603.1
|
| Others |
UniRef100:
UniRef100_Q9ULV5
UniRef90:
UniRef90_Q9ULV5
UniRef50:
UniRef50_Q9ULV5
UniGene:
Hs.512156,
Hs.710714
CCDS:
CCDS45510.1,
CCDS42175.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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