| Type | Description |
|---|---|
| Definition | transmembrane protein 67 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:12:00 | The ciliary Frizzled-like receptor Tmem67 regulates canonical Wnt/beta-catenin signalling in the developing cerebellum via Hoxb5. | 30931988 |
| 2016-03-05 11:49:00 | Multi-organ developmental abnormalities in the Tmem67(tm1Dgen/H1) knockout mouse that closely resemble those seen in Wnt5a and Ror2 knockout mice. | 26035863 |
| 2015-04-11 13:09:00 | Meckelin is expressed in mESCs and localized at the primary cilium. Meckelin depletion impairs neural differentiation of mESCs. | 24613594 |
| 2014-02-22 12:13:00 | TMEM67 mutations cause PKD through ERK- and JNK-dependent signalling pathways, which may provide novel insight into the therapy of polycystic kidney diseases. | 23456819 |
| 2013-11-02 11:33:00 | The Meckel syndrome protein meckelin (TMEM67) is a key regulator of cilia function but is not required for tissue planar polarity. | 23393159 |
| Type | IDs |
|---|---|
| Synonymous | 5330408M12Rik, B230117O07, b2b1163.1Clo, b2b1291.1Clo |
| Gene |
UniProtKB-ID:
MKS3_MOUSE,
A2AJP5_MOUSE,
E9QNI1_MOUSE
UniprotKB:
Q8BR76,
A2AJP5,
E9QNI1
UniParc:
UPI00006A77FB,
UPI000059DEEF,
UPI00006A77FA,
UPI000024E7F5
EMBL:
AK042835,
AK045429,
AL772167
Ensembl:
ENSMUSG00000049488
KO:
mmu:329795
|
| Nucleutide sequences |
EMBL-CDS:
BAC31378.1,
BAC32362.1
Ensembl_TRS:
ENSMUST00000108293,
ENSMUST00000050686
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103928,
ENSMUSP00000052644
RefSeq:
XP_006538071.1,
XP_006538070.3,
XP_036020081.1,
NP_808529.3
|
| Others |
UniRef100:
UniRef100_Q8BR76,
UniRef100_A2AJP5
UniRef90:
UniRef90_Q8BR76
UniRef50:
UniRef50_Q8BR76
UniGene:
Mm.475125
CCDS:
CCDS17974.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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