| Type | Description |
|---|---|
| Definition | Ubiquilin |
| Date | Results | Publications |
|---|---|---|
| 2019-04-20 11:23:00 | Data indicate a role for ubiquilins as regulators of autophagy by controlling mTOR serine-threonine kinases (mTOR)signalling. | 30804504 |
| 2018-12-22 10:45:00 | Study demonstrated that the depletion of dUbqn markedly affected the expression and sub-cellular localization of Drosophila TDP-43 (TBPH), resulting in a cytoplasmic ubiquitin-positive TBPH pathology. | 29936333 |
| 2018-10-06 10:52:00 | The genome of Drosophila contains a single UBQLN homolog (dUbqn) that shows high similarity to UBQLN1 and UBQLN2; therefore, the fly is a useful model for characterizing the role of UBQLN in vivo in neurological disorders affecting locomotion and learning abilities. We herein performed a phenotypic and molecular characterization of diverse dUbqn lines | 29247619 |
| 2018-02-17 11:42:00 | Thus, the deubiquitinase Leon maintains ubiquitin homeostasis and proper Ubiquilin levels, preventing postsynaptic proteins from accumulation to confine postsynaptic growth. | 28489002 |
| 2012-01-28 10:57:00 | overexpression of Dsk2 caused severe morphological abnormalities in the late pupal stages, leading to pharate adult lethality, accompanied by a huge accumulation of highly polyubiquitylated proteins. | 21973017 |
| Type | IDs |
|---|---|
| Synonymous | BEST:LD26923, CG14224, Chap, DSK2, Dmel\CG14224, Dsk2, UBQLN homolog, UBQLN1, anon-18DEa, clone 5.42, dUbqln, dUbqn, dsk2, ubqn |
| Gene |
UniProtKB-ID:
Q9VWD9_DROME
UniprotKB:
Q9VWD9
UniParc:
UPI00000777A1
EMBL:
AY128447,
AE014298
EnsemblGenome:
FBgn0031057
KO:
dme:Dmel_CG14224
|
| Nucleutide sequences |
EMBL-CDS:
AAM75040.1,
AHN59927.1,
AAF49003.1
Gene_ORFName:
CG14224,
Dmel_CG14224
EnsemblGenome_TRS:
FBtr0074750,
FBtr0340612
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0074519,
FBpp0309477
RefSeq:
NP_608344.1,
NP_001285457.1
|
| Others |
UniRef100:
UniRef100_Q9VWD9
UniRef90:
UniRef90_Q9VWD9
UniRef50:
UniRef50_Q9VWD9
UniGene:
Dm.11604
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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