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3295 HSD17B4

3295

HSD17B4

hydroxysteroid 17-beta dehydrogenase 4

protein-coding

Homo sapiens

基因描述

Type Description
Definition hydroxysteroid 17-beta dehydrogenase 4

研究结论

Date Results Publications
2021-03-27 14:44:00 Acetylation-mediated degradation of HSD17B4 regulates the progression of prostate cancer. 32678070
2020-05-16 10:11:00 In HEK293 cells, the D-bifunctional protein (HSD17B4) and the peroxisomal ABC transporter ABCD3 are essential in peroxisomal oxidation of lauric and palmitic acid. 30540494
2019-03-09 12:25:00 HSD17B4 overexpression increased activation. 30747222
2017-11-25 15:10:00 This study reveals a crosstalk between acetylation and chaperone-mediated autophagy degradation in HSD17B4 regulation. 28296597
2017-09-23 10:50:00 we identified that methylation of the promoter CpG island of HSD17B4 was associated with the pathological complete response of HER2-positive breast cancer to trastuzumab and chemotherapy with a specificity of 79% 28186977

名称对应

Type IDs
Synonymous DBP, MFE-2, MPF-2, PRLTS1, SDR8C1
Gene
UniProtKB-ID: DHB4_HUMAN, B2R659_HUMAN, B3KSP2_HUMAN, A0A0S2Z4J1_HUMAN
UniprotKB: P51659, B2R659, B3KSP2, A0A0S2Z4J1
UniParc: UPI0000000C4F, UPI000175057B, UPI0001AE7403, UPI0001D3B611, UPI0000D46BBE
EMBL: AF057729, BC003098, AF057720, AC024564, GQ901009, AF057739, AF057727, AF057740, AF057732, X87176, AK094049, AK298075, AF057726, AK301212, AF057725, AF057736, AF057733, AF057730, AF057722, AK312449, AF057738, KU178135, CH471086, AF057731, AF057728, AF057723, AF057737, AF057735, AF057721, AF057724, AF057734
Ensembl: ENSG00000133835
KO: hsa:3295
Nucleutide sequences
EMBL-CDS: CAA60643.1, BAG62787.1, AAH03098.1, AAD08652.1, BAG60363.1, BAG35356.1, BAG52804.1, ALQ33593.1, ADO22526.1, EAW48911.1
Gene_ORFName: hCG_37330
Ensembl_TRS: ENST00000510025, ENST00000515320, ENST00000414835
Protein sequencees
Ensembl_PRO: ENSP00000424613, ENSP00000424940, ENSP00000411960
RefSeq: NP_001361426.1, NP_000405.1, NP_001278957.1, NP_001186220.1, NP_001361430.1, NP_001278956.1, NP_001361432.1, NP_001361429.1, NP_001361428.1, NP_001186221.1, NP_001361427.1, NP_001361431.1
Others
UniRef100: UniRef100_B3KSP2, UniRef100_B2R659, UniRef100_P51659
UniRef90: UniRef90_P51659, UniRef90_A0A2K6MG97
UniRef50: UniRef50_P51659
UniGene: Hs.406861
CCDS: CCDS4126.1, CCDS56379.1, CCDS56378.1

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