Ppp1r12b - protein phosphatase 1, regulatory subunit 12B-BMKCloudï½ç¾è¿å®¢äº

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329251 Ppp1r12b

基因描述

Type	Description
Definition	protein phosphatase 1, regulatory subunit 12B

研究结论

Date	Results	Publications
2011-05-10 17:53:00	MYPT2 is truly the regulatory subunit of cardiac myosin phosphatase in-vivo and plays a significant role in modulating cardiac function.	19966500

名称对应

Type	IDs
Synonymous	1810037O03Rik, 9530009M10Rik, AI132431, Mypt2
Gene	UniProtKB-ID: A6H644_MOUSE, A0A571BGD8_MOUSE UniprotKB: A6H644, A0A571BGD8 UniParc: UPI0000511B97, UPI0000D62D67 EMBL: AC131591, AC117827, BC145746 Ensembl: ENSMUSG00000073557 KO: mmu:329251
Nucleutide sequences	EMBL-CDS: AAI45747.1 Ensembl_TRS: ENSMUST00000086444, ENSMUST00000168381, ENSMUST00000238280
Protein sequencees	Ensembl_PRO: ENSMUSP00000131406, ENSMUSP00000083633, ENSMUSP00000158804 RefSeq: XP_017176768.1, NP_001355756.1, XP_036021781.1, XP_006529770.1, XP_017176766.1, XP_017176767.1, NP_001074776.1, XP_006529776.1, NP_001355758.1
Others	UniRef100: UniRef100_A6H644, UniRef100_A0A571BGD8 UniRef90: UniRef90_Q8BG95, UniRef90_A0A2K6EFC6 UniRef50: UniRef50_F7EGT7, UniRef50_O60237-3 UniGene: Mm.188709, Mm.451578

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Ensembl: {{protein.proteinEnsembl}}

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Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
31883643	Loss-of-Function Variants in PPP1R12A: From Isolated Sex Reversal to Holoprosencephaly Spectrum and Urogenital Malformations. Am J Hum Genet Joel J Hughes , Ebba Alkhunaizi , Paul Kruszka , Louise C Pyle , Dorothy K Grange , Seth I Berger , Katelyn K Payne , Diane Masser-Frye , Tommy Hu , Michelle R Christie , Nancy J Clegg , Joshua L Everson , Ariel F Martinez , Laurence E Walsh , Emma Bedoukian , Marilyn C Jones , Catharine Jean Harris , Korbinian M Riedhammer , Daniela Choukair , Patricia Y Fechner , Meilan M Rutter , Sophia B Hufnagel , Maian Roifman , Gad B Kletter , Emmanuele Delot , Eric Vilain , Robert J Lipinski , Chad M Vezina , Maximilian Muenke , David Chitayat	2020-01-02	-
29669786	Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression. Circulation David Y Chiang , Katherina M Alsina , Eleonora Corradini , Martin Fitzpatrick , Li Ni , Satadru K Lahiri , Julia O Reynolds , Xiaolu Pan , Larry Scott , Albert J R Heck , Xander H T Wehrens	2018-10-09	-
29518331	Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner. J. Proteome Res. Paul R Evans , Kyle J Gerber , Eric B Dammer , Duc M Duong , Devrishi Goswami , Daniel J Lustberg , Juan Zou , Jenny J Yang , Serena M Dudek , Patrick R Griffin , Nicholas T Seyfried , John R Hepler	2018-04-06	-
29254152	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry. Oncotarget Maria Del Mar Masdeu , Beatriz G ArmendÃ¡riz , Anna La Torre , Eduardo Soriano , Ferran Burgaya , JesÃºs Mariano UreÃ±a	2017-11-24	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
19966500	Overexpression of myosin phosphatase reduces Ca(2+) sensitivity of contraction and impairs cardiac function. Circ. J. Hideo Mizutani , Ryuji Okamoto , Nobuyuki Moriki , Katsuhisa Konishi , Masaya Taniguchi , Satoshi Fujita , Kaoru Dohi , Katsuya Onishi , Noboru Suzuki , Shinji Satoh , Naoki Makino , Takeo Itoh , David J Hartshorne , Masaaki Ito	2010-01-01	-
20059953	A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell Shigetoshi Yokoyama , Yoshiaki Ito , Hiroe Ueno-Kudoh , Hirohito Shimizu , Kenta Uchibe , Sonia Albini , Kazuhiko Mitsuoka , Shigeru Miyaki , Minako Kiso , Akane Nagai , Tomohiro Hikata , Tadahiro Osada , Noritsugu Fukuda , Satoshi Yamashita , Daisuke Harada , Valeria Mezzano , Masataka Kasai , Pier Lorenzo Puri , Yoshihide Hayashizaki , Haruo Okado , Megumi Hashimoto , Hiroshi Asahara	2009-12-01	-
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-

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