| Type | Description |
|---|---|
| Definition | Vav guanine nucleotide exchange factor |
| Date | Results | Publications |
|---|---|---|
| 2015-07-25 11:06:00 | Findings establish that Vav acts at multiple times during eye development to prevent excessive cell recruitment by limiting EGFR signalling and by regulating junction dynamics to ensure the correct patterning and morphogenesis of the Drosophila eye. | 25813543 |
| 2013-12-21 10:48:00 | regulator of Rac activity in a developmentally regulated cell migration | 23525006 |
| 2010-03-08 12:11:00 | vav acts in coordination with other GEFs to regulate axon growth and guidance during development by linking guidance signals to the cytoskeleton via the modulation of Rac activity | 20147552 |
| 2010-01-21 00:00:00 | DroVav has a role as a signal transducer that participates in receptor tyrosine kinase pathways and functions as a GEF for the small RhoGTPase, DRac | 14555990 |
| Type | IDs |
|---|---|
| Synonymous | BcDNA:GH01128, CG7893, DmVav, Dmel\CG7893, DroVav, vav |
| Gene |
UniProtKB-ID:
VAV_DROME,
A8JUQ9_DROME,
M9PHJ6_DROME
UniprotKB:
Q9NHV9,
A8JUQ9,
M9PHJ6
UniParc:
UPI0002943678,
UPI00000072E3,
UPI0000EFD3AF,
UPI00015D9B7D
EMBL:
AF218780,
AE014298,
AY095173,
BT029984,
AY069536
EnsemblGenome:
FBgn0040068
KO:
dme:Dmel_CG7893
|
| Nucleutide sequences |
EMBL-CDS:
AAF48943.3,
AAF28765.1,
ABM92858.1,
AAN09485.1,
AAL39681.1,
AAM12266.1,
ABW09454.1,
AGB95543.1
Gene_ORFName:
CG7893,
Dmel_CG7893,
CG7893,
Dmel_CG7893,
CG7893
EnsemblGenome_TRS:
FBtr0074678,
FBtr0074677,
FBtr0113316,
FBtr0333759
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0074449,
FBpp0074448,
FBpp0112228,
FBpp0305901
RefSeq:
NP_728235.1,
NP_573372.1,
NP_001097030.1,
NP_001259703.1
|
| Others |
UniRef100:
UniRef100_M9PHJ6,
UniRef100_A8JUQ9,
UniRef100_Q9NHV9
UniRef90:
UniRef90_A8JUQ9,
UniRef90_Q9NHV9
UniRef50:
UniRef50_A8JUQ9,
UniRef50_Q9NHV9
UniGene:
Dm.218
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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