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3292 HSD17B1

3292

HSD17B1

hydroxysteroid 17-beta dehydrogenase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition hydroxysteroid 17-beta dehydrogenase 1

研究结论

Date Results Publications
2021-01-23 12:57:00 Altered expression of 17betahydroxysteroid dehydrogenase type 2 and its prognostic significance in nonsmall cell lung cancer. 32236582
2020-05-16 11:33:00 a new inhibitor is proposed that may inhibit 17b-HSD1 through the formation of a dead-end complex. This finding indicates a simple mechanism of enzyme regulation in the physiological background and introduces a pioneer inhibitor of 17b-HSD1 based on the dead-end inhibition model for efficiently targeting estrogen-dependent diseases 30768851
2019-08-31 12:57:00 Aberrant ERRgamma expression may contribute to the pathogenesis of FGR by regulating the transcriptional activity of HSD17B1. 29941172
2018-01-20 10:35:00 Our genetic study demonstrated HSD17B1 937 G variant as a risk factor for infertility in women with stage I and II endometriosis in Polish Caucasian patients. 28405865
2017-11-04 12:15:00 HSD17B1 is a promising marker to predict EC prognosis. 27923582

名称对应

Type IDs
Synonymous 17-beta-HSD, 20-alpha-HSD, E2DH, EDH17B2, EDHB17, HSD17, SDR28C1
Gene
UniProtKB-ID: DHB1_HUMAN, A0A0A0MQS7_HUMAN
UniprotKB: P14061, A0A0A0MQS7
UniParc: UPI00001AE658, UPI0000D4CD19
EMBL: M84472, M36263, BC111935, M27138, BC104752, U34879, X13440, CH471152, AK127832, AC067852
Ensembl: ENSG00000108786
KO: hsa:3292
Nucleutide sequences
EMBL-CDS: AAB16942.1, AAI11936.1, AAB16941.1, EAW60836.1, AAA35600.1, AAD05019.1, CAA31792.1, BAG54583.1, AAI04753.1
Ensembl_TRS: ENST00000585807, ENST00000225929
Protein sequencees
Ensembl_PRO: ENSP00000466799, ENSP00000225929
RefSeq: NP_000404.2, NP_001317148.1
Others
UniRef100: UniRef100_P14061, UniRef100_A0A0A0MQS7
UniRef90: UniRef90_P14061
UniRef50: UniRef50_P14061
UniGene: Hs.654385, Hs.655222
CCDS: CCDS11428.1

全选

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