| Type | Description |
|---|---|
| Definition | polycystic kidney disease 2-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 11:44:00 | PKD2L1 deficiency increased p300-mediated acetylation of histone 3 lysine 27 on the promoter of sodium/calcium exchange 1 (NCX1) by repressing AMP-activated protein kinase (AMPK) activity, resulting in NCX1 overexpression and mitochondrial Ca(2+) overload. | 30089272 |
| 2018-12-22 11:46:00 | The pore helix and transmembrane segment 6 of PKD2L1 are involved in upper and lower-gate opening, adopt an open conformation. | 29567962 |
| 2016-12-17 10:53:00 | In epileptic seizures mouse model, Pkdl deficiency leads to the loss of beta2AR on neuronal cilia, reduction in cAMP levels in the central nervous system, and reduction in the activation of cAMP response element-binding protein. | 26612203 |
| 2016-10-08 12:27:00 | This study demonstrated that spontaneously active unitary currents in CSF-cNs are due to PKD2L1 channels that are capable, with a single opening, of triggering action potentials | 26220314 |
| 2015-09-26 13:25:00 | sour taste cells in the posterior tongue express a proton current; the current is present in PKD2L1-expressing taste cells from circumvallate, foliate, and fungiform papillae but not in a variety of other cells | 25857556 |
| Type | IDs |
|---|---|
| Synonymous | B830002B15, BC046386, PCL, PKD2L, Pkdl, TRPP3 |
| Gene |
UniProtKB-ID:
PK2L1_MOUSE
UniprotKB:
A2A259
UniParc:
UPI00001EC613
EMBL:
AB290927,
BC116297,
AF271381,
AC125101,
BC116323
Ensembl:
ENSMUSG00000037578
KO:
mmu:329064
|
| Nucleutide sequences |
EMBL-CDS:
AAK58371.1,
AAI16324.2,
BAF45380.1,
AAI16298.1
Ensembl_TRS:
ENSMUST00000042026
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000045675
RefSeq:
XP_011245569.1,
XP_036017506.1,
XP_006527206.1,
NP_852087.2,
XP_036017505.1
|
| Others |
UniRef100:
UniRef100_A2A259
UniRef90:
UniRef90_A2A259
UniRef50:
UniRef50_Q9P0L9
UniGene:
Mm.308481
CCDS:
CCDS29846.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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