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328795 Ubash3a

328795

Ubash3a

ubiquitin associated and SH3 domain containing, A

protein-coding

Mus musculus

基因描述

Type Description
Definition ubiquitin associated and SH3 domain containing, A

研究结论

Date Results Publications
2020-12-26 13:12:00 UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice. 32694640
2019-07-27 12:08:00 Bone marrow-derived dendritic cells (BMDCs) lacking ubiquitin associated and SH3 domain containing A (Sts-2) expression have an enhanced ability to inhibit Candida albicans growth and contribute significantly to the resistance of Sts-/- mice. Within BMDCs, the Sts phosphatases negatively regulate the activation of select pathways downstream of the key fungal pathogen pattern recognition receptor Dectin-1. 30018105
2018-10-13 11:21:00 STS-2 suppresses development of collagen-induced arthritis. 28972439
2017-09-09 11:55:00 Herein, the authors demonstrate that mice lacking Sts expression are significantly resistant to infection by the live vaccine strain of Francisella tularensis. 28630061
2017-08-31 12:53:00 Sts-1 and Sts-2 are not required for the immune control of murine herpesvirus 68 in a normal course of gammaherpesvirus infection. 24587276

名称对应

Type IDs
Synonymous 5830413C03Rik, C330001M22, Sts-2, TULA, TULA-1
Gene
UniProtKB-ID: UBS3A_MOUSE, A0A498WGR9_MOUSE
UniprotKB: Q3V3E1, A0A498WGR9
UniParc: UPI00005AB664, UPI0003D709FC
EMBL: AK041690, AK169696, AC167247, AC154652, CU024900
Ensembl: ENSMUSG00000042345
KO: mmu:328795
Nucleutide sequences
EMBL-CDS: BAE20600.1, BAE41311.1
Gene_ORFName: Sts2
Ensembl_TRS: ENSMUST00000236745, ENSMUST00000048656
Protein sequencees
Ensembl_PRO: ENSMUSP00000158544, ENSMUSP00000045890
RefSeq: XP_006524497.1, NP_808491.2
Others
UniRef100: UniRef100_A0A498WGR9, UniRef100_Q3V3E1
UniRef90: UniRef90_Q3V3E1
UniRef50: UniRef50_P57075
UniGene: Mm.387930
CCDS: CCDS50054.1

全选

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