| Type | Description |
|---|---|
| Definition | fused |
| Date | Results | Publications |
|---|---|---|
| 2015-04-25 12:26:00 | Data show that normal Ci-155 activation by Hh requires Cos2 binding to Fu, supporting the hypothesis that Cos2 mediates the apposition of Fu molecules suitable for cross-phosphorylation and consequent full activation of Fu kinase. | 25633354 |
| 2012-01-21 10:20:00 | Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus. | 21844892 |
| 2011-11-26 10:35:00 | Hh-induced Smo conformational change facilitates the assembly of active Smo-Cos2-Fu signaling complexes that promote Fu kinase domain dimerization, phosphorylation and activation; Fu regulates both the activator and repressor forms of Ci | 21852395 |
| 2011-01-22 10:18:00 | Study shows that Fused (Fu), a serine/threonine kinase that regulates Hedgehog, functions in concert with the E3 ligase Smurf to regulate ubiquitination and proteolysis of the BMP receptor Thickveins in germline stem cells daughter cystoblasts. | 21145463 |
| 2010-01-21 00:00:00 | model in which Hedgehog signals at least twice in germarial somatic cells: through a fused-independent pathway to control somatic stem cell proliferation; and through a classical fused-dependent pathway to regulate prefollicular cell differentiation | 12163413 |
| Type | IDs |
|---|---|
| Synonymous | CG6551, Dm fu, Dmel\CG6551, FU, Fu, d Fu, dFu, fu[mel], l(1)fu |
| Gene |
UniProtKB-ID:
FUSED_DROME
UniprotKB:
P23647
UniParc:
UPI000012AD97
EMBL:
X55759,
S69165,
X80468,
AE014298,
S69166,
L34782
KO:
dme:Dmel_CG6551
|
| Nucleutide sequences |
EMBL-CDS:
AAB29840.1,
CAA39285.1,
AAF48871.1,
CAA56640.1,
AAB29841.1,
AAA28552.1
Gene_ORFName:
CG6551
|
| Protein sequencees |
RefSeq:
NP_477499.1
|
| Others |
UniRef100:
UniRef100_P23647
UniRef90:
UniRef90_P23647
UniRef50:
UniRef50_P23647
UniGene:
Dm.17302
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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