例如:"NBL1", "4681", "drought"
收藏
3284 HSD3B2

3284

HSD3B2

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2

研究结论

Date Results Publications
2018-10-20 10:29:00 Independent silencing of CRY1 and CRY2 genes in HAC15 cells resulted in a mild upregulation of HSD3B2 without affecting HSD3B1 expression. In conclusion, our results support the hypothesis that CRY1 and CRY2, being AngII-regulated genes, and showing a differential expression in APAs when compared with the adjacent adrenal cortex, might be involved in adrenal cell function, and in the regulation of aldosterone production 29874863
2018-07-28 11:38:00 Observed significant increase in HSD3B2 and ESR1 transcripts in follicular eutropic endometrium from infertile women with endometriosis may be related to abnormal biological effect of E2 in endometrium, further affecting the development of human embryos. 29664547
2017-11-26 01:15:00 mRNAs expression and methylation pattern of RARB, NR4A1 and HSD3B2 genes in human adrenal tissues (HAT) and in pediatric virilizing adrenocortical tumors (VAT) were analyzed. 27670690
2017-07-08 12:04:00 Sequencing analyses indicate homozygous p.W355R mutation at exon 4 of the 3 beta-hydroxysteroid dehydrogenase type II (HSD3beta2) gene in both siblings. 27476613
2017-04-08 11:10:00 the first HSD3B2 gene mutation in the Italian population and analyzed its effect in the context of the 3beta-HSD2 structure and function. 27082427

名称对应

Type IDs
Synonymous HSD3B, HSDB, SDR11E2
Gene
UniProtKB-ID: 3BHS2_HUMAN, A0A024R0F9_HUMAN
UniprotKB: P26439, A0A024R0F9
UniParc: UPI0000001C6C, UPI0000401FC7
EMBL: BC038419, CH471122, CR627415, AK222997, BC131488, M77144, S80140, AL359553, S60309, M67466, S60310
Ensembl: ENSG00000203859
KO: hsa:3284
Nucleutide sequences
EMBL-CDS: AAD14329.1, AAC60600.1, AAI31489.1, AAA36016.1, BAD96717.1, CAH10504.1, EAW56700.1, AAH38419.1, AAC60599.1, AAA36014.1, EAW56701.1, EAW56702.1
Gene_ORFName: hCG_38656
Ensembl_TRS: ENST00000369416, ENST00000543831
Protein sequencees
Ensembl_PRO: ENSP00000445122, ENSP00000358424
RefSeq: NP_001159592.1, NP_000189.1
Others
UniRef100: UniRef100_P26439
UniRef90: UniRef90_P26439
UniRef50: UniRef50_P22071
UniGene: Hs.654399
CCDS: CCDS902.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员