| Type | Description |
|---|---|
| Definition | hes family bHLH transcription factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:13:00 | IL-6 and IL-8, secreted by myofibroblasts in the tumor microenvironment, activate HES1 to expand the cancer stem cell population in early colorectal tumor. | 33544929 |
| 2021-03-06 13:26:00 | Hes1 Is Essential in Proliferating Ductal Cell-Mediated Development of Intrahepatic Cholangiocarcinoma. | 33067264 |
| 2020-12-12 13:29:00 | MYEOV increases HES1 expression and promotes pancreatic cancer progression by enhancing SOX9 transactivity. | 32879444 |
| 2020-12-12 13:26:00 | Inhibition of NOTCH signaling pathway chemosensitizes HCC CD133(+) cells to vincristine and 5-fluorouracil through upregulation of BBC3. | 32173531 |
| 2020-09-05 13:58:00 | Inhibition of HES-1 might play a protective role in endothelial cells under cholesterol stimulation via PI3K/AKT signaling pathway. | 32329442 |
| Type | IDs |
|---|---|
| Synonymous | HES-1, HHL, HRY, bHLHb39 |
| Gene |
UniProtKB-ID:
HES1_HUMAN
UniprotKB:
Q14469
UniParc:
UPI0000037B01
EMBL:
AF264785,
CR541843,
AK000415,
L19314
Ensembl:
ENSG00000114315
KO:
hsa:3280
|
| Nucleutide sequences |
EMBL-CDS:
CAG46641.1,
AAA65220.1,
BAA91149.1,
AAF73060.1
Ensembl_TRS:
ENST00000232424
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000232424
RefSeq:
NP_005515.1
|
| Others |
UniRef100:
UniRef100_Q14469
UniRef90:
UniRef90_Q14469
UniRef50:
UniRef50_Q14469
UniGene:
Hs.250666
CCDS:
CCDS3305.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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