| Type | Description |
|---|---|
| Definition | Frequenin 1 |
| Date | Results | Publications |
|---|---|---|
| 2012-12-08 11:04:00 | [review] Stimulation protocols, sources of calcium and expression patterns (presynaptic vs postsynaptic) of Frq may result in the activation of various protein targets, leading to different synaptic effects. | 22396213 |
| 2010-07-26 11:15:00 | Frq modulates Ca(2+) entry through a functional interaction with the alpha(1) voltage-gated Ca(2+)-channel subunit; this interaction regulates neurotransmission and nerve-terminal growth. | 19861494 |
| 2010-04-19 11:28:00 | Synonymous substitutions have been prevalent in the evolution of the coding region of frq1 and frq2, indicating the presence of strong functional constraints following gene duplication. | 20170488 |
| 2010-01-21 00:00:00 | We conclude that Frqs have two distinct functions: one in neurotransmission, regulating the probability of release per synapse, and another in axonal growth and bouton formation. | 17970740 |
| Type | IDs |
|---|---|
| Synonymous | CG5744, Dmel\CG5744, Frq, HL-II, frq, frq1 |
| Gene |
UniProtKB-ID:
FREQ_DROME,
M9PHW6_DROME
UniprotKB:
P37236,
M9PHW6
UniParc:
UPI0000124CE8
EMBL:
AE014298,
L08064
EnsemblGenome:
FBgn0030897
KO:
dme:Dmel_CG5744
|
| Nucleutide sequences |
EMBL-CDS:
ABC67191.1,
AAA28539.1,
AAG22356.1,
AGB95516.1,
AGB95515.1
Gene_ORFName:
CG5744,
CG5744,
Dmel_CG5744
EnsemblGenome_TRS:
FBtr0100239,
FBtr0335120,
FBtr0335119,
FBtr0074545,
FBtr0335119,
FBtr0335120,
FBtr0100239,
FBtr0074545
|
| Protein sequencees |
EnsemblGenome_PRO:
FBpp0074319,
FBpp0307121,
FBpp0307120,
FBpp0099625,
FBpp0074319,
FBpp0307120,
FBpp0307121,
FBpp0099625
RefSeq:
NP_001259673.1,
NP_001259674.1,
NP_001033853.1,
NP_573271.1
|
| Others |
UniRef100:
UniRef100_P37236
UniRef90:
UniRef90_P37236
UniRef50:
UniRef50_P37236
UniGene:
Dm.35315
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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