| Type | Description |
|---|---|
| Definition | ubiquitin specific peptidase 44 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-22 12:58:00 | USP44 is dispensable for the normal physiology of hematopoietic and immune systems, and its functions in these systems are likely redundant with other USP family proteins. | 30639577 |
| 2013-02-09 10:31:00 | USP44 inhibited chromosome segregation errors independent of its role in the mitotic checkpoint by regulating centrosome separation, positioning, and mitotic spindle geometry. | 23187126 |
| 2011-12-24 10:53:00 | These data are consistent with an important role for USP44 in regulating Cdc20-APC/C activity and suggest that high levels of this enzyme may contribute to the pathogenesis of T-cell leukemias. | 21853124 |
| Type | IDs |
|---|---|
| Synonymous | E430004F17Rik |
| Gene |
UniProtKB-ID:
UBP44_MOUSE
UniprotKB:
Q8C2S0
UniParc:
UPI00020A9667
EMBL:
CJ236846,
AC124686,
AK088109,
BC111886
Ensembl:
ENSMUSG00000020020
KO:
mmu:327799
|
| Nucleutide sequences |
EMBL-CDS:
BAC40148.1,
AAI11887.1
Ensembl_TRS:
ENSMUST00000216224
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000149020
RefSeq:
NP_001193780.1,
XP_030100996.1,
NP_001363910.1,
XP_011241786.1,
XP_030100994.1,
XP_011241783.1,
XP_011241790.1,
XP_036011718.1,
XP_030100995.1,
XP_011241787.1,
XP_011241785.1,
XP_011241784.1,
XP_011241788.1,
XP_011241782.1,
XP_011241792.1,
XP_011241789.1,
XP_011241791.1
|
| Others |
UniRef100:
UniRef100_Q8C2S0
UniRef90:
UniRef90_Q8C2S0
UniRef50:
UniRef50_Q9H0E7
UniGene:
Mm.491598
CCDS:
CCDS88075.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32644293 |
The deubiquitinase USP44 promotes Treg function during inflammation by preventing FOXP3 degradation. EMBO Rep Jing Yang , Ping Wei , Joseph Barbi , Qianru Huang , Evan Yang , Yakun Bai , Jia Nie , Yanhang Gao , Jinhui Tao , Ying Lu , Chichu Xie , Xiaoxia Hou , Jiazi Ren , Xingmei Wu , Jian Meng , Ying Zhang , Juan Fu , Wei Kou , Yayi Gao , Zuojia Chen , Rui Liang , Andy Tsun , Dan Li , Wenzhi Guo , Shuijun Zhang , Song-Guo Zheng , Junqi Niu , Paul Galardy , Xuemei Tong , Guochao Shi , Huabin Li , Fan Pan , Bin Li |
2020-09-03 | - |
| 30639577 |
Exp. Hematol. Yun Hsiao Lin , Michael Forster , Yue Liang , Mansen Yu , HanChen Wang , Francis Robert , David Langlais , Jerry Pelletier , Simon Clare , Anastasia Nijnik |
2019-04-01 | - |
| 26811477 |
Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling. Proc. Natl. Acad. Sci. U.S.A. Akhee S Jahan , Maxime Lestra , Lee Kim Swee , Ying Fan , Mart M Lamers , Fikadu G Tafesse , Christopher S Theile , Eric Spooner , Roberto Bruzzone , Hidde L Ploegh , Sumana Sanyal |
2016-02-09 |
Otub1,
Usp34,
Ubc,
Usp12,
Usp4,
Usp9x,
Usp7,
Usp25,
Usp44,
Usp24,
Uchl3,
Uchl5,
Usp46,
Cyld,
USP12,
LAT,
GRB2,
TRAT1,
WDR48,
USP46,
ZAP70,
ITCH,
CBLB,
WDR20
|
| 23187126 |
USP44 regulates centrosome positioning to prevent aneuploidy and suppress tumorigenesis. J. Clin. Invest. Ying Zhang , Oded Foreman , Dennis A Wigle , Farhad Kosari , George Vasmatzis , Jeffrey L Salisbury , Jan van Deursen , Paul J Galardy |
2012-12-01 | - |
| 22681888 |
RNF20 and USP44 regulate stem cell differentiation by modulating H2B monoubiquitylation. Mol. Cell Gilad Fuchs , Efrat Shema , Rita Vesterman , Eran Kotler , Zohar Wolchinsky , Sylvia Wilder , Lior Golomb , Ariel Pribluda , Feng Zhang , Mahmood Haj-Yahya , Ester Feldmesser , Ashraf Brik , Xiaochun Yu , Jacob Hanna , Daniel Aberdam , Eytan Domany , Moshe Oren |
2012-06-08 |
Rnf20,
Usp44
|
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 21853124 |
PLoS ONE Ying Zhang , Jan van Deursen , Paul J Galardy |
2011-01-01 |
Usp44,
USP44
|
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 16141073 |
Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G Engström , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium |
2005-09-02 |
Gm14018,
Gm14964,
F630206G17Rik,
Oog3,
Notumos,
Ldlrap1,
Mdn1,
Pydc3,
9330171B17Rik,
Mfap1b,
Tmsb15b2,
Gm12802,
E430020m11rik,
Gm11335,
Gm15772,
Gm17762,
A930017K11Rik,
LOC100036513,
Gata5os,
Umad1,
Gm16982,
Gm9887,
Gm9872,
LOC100036530,
Gm9934,
Gm9913,
Gm11149,
BC028777,
Gm13999,
LOC100036540,
Gm9744,
Gm9983,
D630002J18Rik,
Gm16525,
Gm11696,
Dnajc3,
9430060I03Rik,
Gm12359,
4921516A02Rik,
Fam129c,
Gm10589,
Rsph3b,
Rnaset2a,
5430403G19Rik,
D030047H15Rik,
Gm13274,
B930046K06Rik,
Gm10862,
Gm10792,
Gm10802,
Gm10532,
G730003C15Rik,
Runx2os1,
Gm15612,
Gm10856,
Gm10857,
Gm10685,
Gm10803,
Gm10723,
F630028O10Rik,
Gm10836,
Gm10405,
Gm10513,
Gm10609,
F630201L12Rik,
4932427H20Rik,
Zfp389,
Gm10763,
Gm10062,
Gm10714,
Gm10531,
Gm10876,
Gm10750,
Gm10433,
Gm10837,
Gm10647,
Gm10648,
Gm10650,
Gm10610,
F830115B05Rik,
Gm10473,
Gm10614,
Gm10286,
G730046D07Rik,
Gm10287,
Gm10785,
Gm10183,
Gm10512,
1700061E17Rik,
Gm44113,
Gm10579,
Gm10741,
Gm10827,
Gm10522,
Gm10536,
Gm15998,
Faddos,
D130050E23Rik,
Gm10735
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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