| Type | Description |
|---|---|
| Definition | DNA replication helicase/nuclease 2 |
| Date | Results | Publications |
|---|---|---|
| 2016-09-03 10:43:00 | The authors establish that a second Dna2-Rpa interaction is mutually exclusive with Rpa-DNA interactions and mediates the displacement of Rpa from ssDNA. | 26491943 |
| 2013-07-27 12:26:00 | DNA2 helicase cleaves G-quadruplex DNA and is required for telomere integrity.DNA2 reduces replication stress at telomeres, thereby preserving genome stability and suppressing cancer development. | 23604072 |
| 2011-09-10 12:10:00 | Characterization of the endonuclease and ATP-dependent flap endo/exonuclease of Dna2. | 21572043 |
| Type | IDs |
|---|---|
| Synonymous | Dna2l, E130315B21Rik |
| Gene |
UniProtKB-ID:
DNA2_MOUSE
UniprotKB:
Q6ZQJ5
UniParc:
UPI0000D6337B,
UPI0000DA6C28
EMBL:
BC115716,
AK028381,
BC025182,
AK129051
Ensembl:
ENSMUSG00000036875
KO:
mmu:327762
|
| Nucleutide sequences |
EMBL-CDS:
BAC25919.1,
AAH25182.1,
BAC97861.1,
AAI15717.1
Ensembl_TRS:
ENSMUST00000092462,
ENSMUST00000131422
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000090119,
ENSMUSP00000115750
RefSeq:
NP_796346.2,
XP_036011717.1
|
| Others |
UniRef100:
UniRef100_Q6ZQJ5
UniRef90:
UniRef90_Q6ZQJ5
UniRef50:
UniRef50_P51530
UniGene:
Mm.21492
CCDS:
CCDS35923.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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