| Type | Description |
|---|---|
| Definition | protein arginine methyltransferase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:26:00 | PRMT2 accelerates tumorigenesis of hepatocellular carcinoma by activating Bcl2 via histone H3R8 methylation. | 32574605 |
| 2019-08-10 11:02:00 | PRMT2beta suppressed glycolytic pathway in MCF7 cells. | 30883646 |
| 2019-05-04 12:38:00 | PRMT2 acts as a transcriptional co-activator for oncogenic gene expression programs in glioblastoma pathogenesis. | 30382083 |
| 2018-09-22 11:09:00 | Results show that tamoxifen resistance in breast cancer cells is connected with the downregulation of PRMT2 and the upregulation of ER-alpha36. Moreover, PRMT2 was able to interact with ER-alpha36 directly, suppress ER-alpha36 and downstream PI3K/Akt and MAPK/ERK signaling, reversing the tamoxifen resistance of breast cancer cells. | 29620287 |
| 2018-07-28 11:32:00 | Low splice variant of PRMT2 expression is associated with breast cancer. | 28677794 |
| Type | IDs |
|---|---|
| Synonymous | HRMT1L1 |
| Gene |
UniProtKB-ID:
ANM2_HUMAN,
A0A0S2Z3N3_HUMAN
UniprotKB:
P55345,
A0A0S2Z3N3
UniParc:
UPI000188F40B,
UPI000057649A,
UPI0000207094,
UPI000020709E,
UPI0000125B21,
UPI000188F40C,
UPI00000738A3
EMBL:
AP000340,
FJ436412,
FJ436411,
U80213,
AL109794,
AP000339,
U79286,
BC000727,
CR541804,
KU178127,
BC100026,
X99209,
AY786414,
AK123650,
FJ436410,
CH471079
Ensembl:
ENSG00000160310
KO:
hsa:3275
|
| Nucleutide sequences |
EMBL-CDS:
ACJ66867.1,
AAI00027.1,
AAV48568.2,
AAB48437.1,
CAG46603.1,
EAX09259.1,
EAX09265.1,
ACJ66868.1,
ACJ66866.1,
AAH00727.1,
AAB50221.1,
CAA67599.1,
BAG53931.1,
CAB52454.1,
ALQ33585.1
Ensembl_TRS:
ENST00000397637,
ENST00000334494,
ENST00000458387,
ENST00000440086,
ENST00000451211,
ENST00000397638,
ENST00000355680,
ENST00000291705
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000407463,
ENSP00000291705,
ENSP00000397266,
ENSP00000335490,
ENSP00000347906,
ENSP00000411984,
ENSP00000380760,
ENSP00000380759
RefSeq:
XP_016883829.1,
XP_005261168.1,
NP_001273607.1,
XP_016883828.1,
NP_001273605.1,
NP_001229794.1,
NP_996845.1,
NP_001229793.1,
XP_006724063.1,
XP_006724062.1,
NP_001273606.1,
XP_006724061.1,
NP_001229795.1,
NP_001526.2
|
| Others |
UniRef100:
UniRef100_P55345
UniRef90:
UniRef90_P55345
UniRef50:
UniRef50_P55345
UniGene:
Hs.154163
CCDS:
CCDS56220.1,
CCDS56219.1,
CCDS74806.1,
CCDS68231.1,
CCDS68230.1,
CCDS13737.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员