例如:"NBL1", "4681", "drought"
收藏
3274 HRH2

3274

HRH2

histamine receptor H2

protein-coding

Homo sapiens

基因描述

Type Description
Definition histamine receptor H2

研究结论

Date Results Publications
2019-07-20 11:47:00 Histamine H2 receptor stimulation upregulates TH2 chemokine CCL17 production in human M2a macrophages. 28728999
2019-05-04 10:16:00 The presence of a minor allele at rs2241562 was associated with increased HF incidence in Chinese participants. Differences in myocardial HRH2 transcript abundance were seen in participants with dilated cardiomyopathy who responded to beta blockade compared to those who did not. 29191567
2017-11-04 11:54:00 Pharmacological or genetic modulations of H2 and H4 HRs (H2R and H4R) not only suppressed gefitinib-induced cytostasis and differentiation of AML cells but also blocked EGFR and ERK1/2 inhibition in MDA-MB-231 cells 27180173
2016-12-17 11:28:00 The T allele of rs3787429 exhibited protective effect against CHF under the dominant and additive models , while, for SNPs in HRH2, DAO, and HNMT, no significant associations were observed in the present study 26989676
2016-10-08 10:09:00 High constitutive Akt2 activity in U937 promonocytes: effective reduction of Akt2 phosphorylation by the histamine H2-receptor and the beta2-adrenergic receptor 26475619

名称对应

Type IDs
Synonymous H2R, HH2R
Gene
UniProtKB-ID: HRH2_HUMAN, A0A1B0GTK7_HUMAN
UniprotKB: P25021, A0A1B0GTK7
UniParc: UPI00000007CC, UPI0000D6DFEA, UPI00001B2326
EMBL: AY136744, D49783, M64799, X98133, CH471062, AB023486, BC054510, AB451483, AC010219, AB041384
Ensembl: ENSG00000113749
KO: hsa:3274
Nucleutide sequences
EMBL-CDS: BAA94469.1, BAA08618.1, CAA66832.1, AAN01270.1, BAG70297.1, AAH54510.1, BAA84279.1, EAW61369.1, AAA58647.1
Ensembl_TRS: ENST00000377291, ENST00000231683, ENST00000636584
Protein sequencees
Ensembl_PRO: ENSP00000231683, ENSP00000366506, ENSP00000489742
RefSeq: XP_006714927.1, XP_011532850.1, NP_001124527.1, XP_016864915.1, NP_001354640.1, XP_006714928.1, XP_011532851.1
Others
UniRef100: UniRef100_P25021, UniRef100_A0A1B0GTK7
UniRef90: UniRef90_P25021
UniRef50: UniRef50_P25021
UniGene: Hs.247885
CCDS: CCDS47344.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员