| Type | Description |
|---|---|
| Definition | histamine receptor H1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:25:00 | Human H1 receptor (HRH1) gene polymorphism is associated with the severity of side effects after desloratadine treatment in Chinese patients with chronic spontaneous uticaria. | 31406237 |
| 2020-11-28 13:12:00 | Upregulation of histamine receptor H1 promotes tumor progression and contributes to poor prognosis in hepatocellular carcinoma. | 31740780 |
| 2020-01-04 10:05:00 | HRH1 gene polymorphisms may correlate with oral H1-antihistamine efficacy for the treatment of patients with allergic rhinitis, which can be used as a biological indicator of the prediction of therapeutic efficacy of patients with allergic rhinitis. | 30168182 |
| 2019-06-15 13:01:00 | Study identified HRH1 as a receptor frequently overexpressed in basal and HER2-targeted therapy-resistant breast cancer (BC) cells, demonstrating that HRH1 inhibition culminates in apoptotic death and hampers tumor growth. ERK activation was identified as the mechanism through which HRH1 blockade signals to promote death in basal BC cells. | 29548821 |
| 2018-05-26 10:49:00 | H1R and H4R are useful biomarkers of allergic inflammation on the ocular surface. Most notably, H4R expressed on eosinophils is useful as a biomarker of eosinophilic inflammation of the ocular surface. | 28391980 |
| Type | IDs |
|---|---|
| Synonymous | H1-R, H1R, HH1R, hisH1 |
| Gene |
UniProtKB-ID:
HRH1_HUMAN
UniprotKB:
P35367
UniParc:
UPI0000050401
EMBL:
D14436,
CH471055,
AY136743,
AB041380,
D28481,
BC060802,
AK289412,
X76786,
AF026261,
Z34897
Ensembl:
ENSG00000196639
KO:
hsa:3269
|
| Nucleutide sequences |
EMBL-CDS:
EAW64092.1,
CAA54182.1,
AAB95156.1,
AAN01269.1,
BAF82101.1,
BAA05840.1,
BAA03319.1,
AAH60802.1,
CAA84380.1,
BAA94465.1
Ensembl_TRS:
ENST00000397056,
ENST00000431010,
ENST00000438284
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000406705,
ENSP00000397028,
ENSP00000380247
RefSeq:
NP_001091681.1,
NP_000852.1,
NP_001091682.1,
NP_001091683.1
|
| Others |
UniRef100:
UniRef100_P35367
UniRef90:
UniRef90_P35367
UniRef50:
UniRef50_P35367
UniGene:
Hs.1570
CCDS:
CCDS2604.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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