| Type | Description |
|---|---|
| Definition | tropomyosin 4 |
| Date | Results | Publications |
|---|---|---|
| 2017-09-09 11:49:00 | findings demonstrate a nonredundant role for TPM4 in platelet biogenesis in humans and mice and reveal that truncating variants in TPM4 cause a previously undescribed dominant Mendelian platelet disorder. | 28134622 |
| 2010-01-21 00:00:00 | These results indicate that Tm-4 plays a role in regulating adhesion structures of osteoclasts, most likely by stabilizing the actin microfilaments present in podosomes and the sealing zone. | 18036591 |
| 2010-01-21 00:00:00 | Tropomyosin 4 defines longitudinal filaments in mouse models of muscular dystrophy and nemaline myopathy. | 17968984 |
| 2010-01-21 00:00:00 | Tm-4 is specifically enriched within and around osteoclast attachment structures, the sealing zone and podosomes. | 16765662 |
| Type | IDs |
|---|---|
| Synonymous | 2610528G24Rik, Tpm4.2, Tpm4.2cy |
| Gene |
UniProtKB-ID:
TPM4_MOUSE
UniprotKB:
Q6IRU2
UniParc:
UPI0000020CDC
EMBL:
BC070421,
BC023701,
BC023827
Ensembl:
ENSMUSG00000031799
KO:
mmu:326618
|
| Nucleutide sequences |
EMBL-CDS:
AAH23701.1,
AAH23827.1,
AAH70421.1
Ensembl_TRS:
ENSMUST00000003575
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003575
RefSeq:
NP_001001491.1
|
| Others |
UniRef100:
UniRef100_Q6IRU2
UniRef90:
UniRef90_P09495
UniRef50:
UniRef50_P09495
UniGene:
Mm.295124
CCDS:
CCDS22408.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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