| Type | Description |
|---|---|
| Definition | ES cell expressed Ras |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:17:00 | ERas regulates cell proliferation and epithelial-mesenchymal transition by affecting Erk/Akt signaling pathway in pancreatic cancer. | 32700262 |
| 2019-11-09 12:18:00 | In summary, these results reveal that inappropriate activation of ERAS may be important in the development of a subset of breast tumors. | 30158566 |
| 2019-03-30 13:06:00 | ERAS may serve as a novel clinical biomarker for PI3K/AKT pathway hyperactivation and HER2-targeted therapy resistance in breast cancer. | 29326437 |
| 2015-08-29 10:42:00 | N-terminal extension of E-RAS is important for E-RAS signaling activity. | 25940089 |
| 2015-05-09 12:38:00 | Expression of ERAS in human melanoma cell lines conferred resistance to PLX4720 and induced hyperphosphorylation of AKT. | 25624498 |
| Type | IDs |
|---|---|
| Synonymous | HRAS2, HRASP |
| Gene |
UniProtKB-ID:
RASE_HUMAN
UniprotKB:
Q7Z444
UniParc:
UPI0000160110
EMBL:
AB093575,
BC101642,
BC101644
Ensembl:
ENSG00000187682
KO:
hsa:3266
|
| Nucleutide sequences |
EMBL-CDS:
BAC76997.1,
AAI01643.1,
AAI01645.1
Ensembl_TRS:
ENST00000338270,
ENST00000636362
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000490793,
ENSP00000339136
RefSeq:
NP_853510.1
|
| Others |
UniRef100:
UniRef100_Q7Z444
UniRef90:
UniRef90_Q7Z444
UniRef50:
UniRef50_Q7Z444
UniGene:
Hs.447330
CCDS:
CCDS35246.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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